摘要
目的优选蜜柚皮中的柚皮苷分离纯化工艺条件。方法以柚皮苷含量为指标,用静态和动态吸附法考察聚酰胺树脂的吸附、解吸性能,并采用响应面实验设计的方法来优化蜜柚皮中柚皮苷的分离纯化条件。结果综合各种因素,选择乙醇浓度为40.0%,洗脱体积为3.5 BV,洗脱流速为0.4 BV·h-1。结论该优化工艺合理,具有可行性,可为提取柚皮苷工业化生产提供一定的理论依据。
Objective To study the purification of naringin in peel of Citrus grandis(L.)Osbec.Methods With naringin as the index,investigate the adsorption and desorption performance of polyamide resin by static and dynamic absorption,response surface method was used to optimize the separation and purification conditions.Results Considering various factors,the alcohol concentration was 40%,the elution volume was 3.5 BV,and the elution flow rate was 0.4 BV·h-1.Conclusion The optimized process is reasonable and feasible,and it can provide a certain theoretical basis for the industrial development and promotion of naringin.
作者
沈晓华
王小平
陈育青
SHEN Xiaohua;WANG Xiaoping;CHEN Yuqing(Pharmacy Department,Zhangzhou Health Vocational College,Fujian Province,Zhangzhou 363000,China)
出处
《中国中医药现代远程教育》
2021年第7期145-148,共4页
Chinese Medicine Modern Distance Education of China
基金
国家中医药管理局全国中药特色技术传承人才培训项目【No.国中医药人教函[2019]43号】
福建省漳州市科学技术局中青年教师教育科研项目(科技类)【No.JAT191424】
福建省漳州市科技局科技重大专项【No.ZZ2018ZD2019】。
关键词
蜜柚皮
分离纯化工艺
聚酰胺树脂
响应面实验
柚皮苷
Citrus grandis(L.)Osbec
purification process
polyamide resin
response surface method
naringin
