摘要
癌症是严重危害人类健康的疾病之一,其发病数和死亡数仍呈持续增加态势,给全球公共卫生系统带来了沉重的负担。在与肿瘤的长期斗争过程中,人们提出了各种各样的方法。100多年前,刚发现伦琴射线不久,人们就开始探索将放射线用于肿瘤的治疗,由此开创了肿瘤放射治疗学。组织间植入放射性粒子治疗肿瘤作为最早开展的近距离放射治疗技术之一,其益处早已得到公众认可,成为肿瘤治疗谱中重要的一员。在放射性粒子植入治疗的实践中,会出现一些粒子离开初始种植位置而到达其他位置的粒子迁移事件。现就恶性肿瘤组织间插植^(125)I粒子、^(125)I粒子迁移及其成因、产生的影响、防护等进行综述。
Cancer is one of the diseases that seriously harm human health.The cancer-related incidence and deaths are still increasing worldwide,which has brought heavy burden to the global public health system.During the long anticancer history,a variety of methods to treat tumors have been developed.More than 100 years ago,shortly after the discovery of Roentgen rays,people began to treat tumors with radiation,and thus pioneered radiation oncology.As a brachytherapy method,implantation of radioactive seeds acts well,has received public recognition,and becomes an important member of the oncology therapeutic spectrum.In vivo,some seeds can migrate from initial site of implantation to other locations.Permanent interstitial brachytherapy and the incidence,mechanism,influence and prevention of ^(125)I seed migration were reviewed here.
作者
朱俊军
葛乃建
杨业发
ZHU Junjun;GE Naijian;YANG Yefa(Eastern Hepatobiliary Intervention Center,the Third Affiliated Hospital of Naval Medical University,Shanghai 201805,China)
出处
《中国癌症杂志》
CAS
CSCD
北大核心
2021年第4期257-262,共6页
China Oncology
基金
国家自然科学基金(31971249)。
