急性缺血性脑卒中氧化应激机制的研究进展

Progress of mechanism of oxidative stress in acute ischemic stroke

脑卒中是我国最主要的疾病死因,而氧化应激贯穿疾病始终。抗氧化应激是重要的防治损伤并促进缺血性脑卒中后神经功能恢复的治疗策略,但其临床应用效果仍不理想。本文就近年急性缺血性脑卒中氧化应激相关机制的研究进展作一综述,以期寻找更好的基础临床转化思路,从而推进对急性缺血性卒中治疗的研究。

Stroke is the leading cause of death in China,while oxidative stress persists throughout the disease.Antioxidative is an important treatment method to prevent nerve injury and promote the recovery of neurological function after ischemic stroke.However,its clinical application effect is still not satisfactory.This article reviews the research progress of oxidative stress related mechanisms in ischemic stroke in recent years,which support finding better transformation ideas,and at last promote the study of treatment of acute ischemic stroke.