体检人群静息心率与2型糖尿病的关系

Relationship Between Resting Heart Rate and Type 2 Diabetes Mellitus in Physical Examination Population

目的分析体检人群静息心率与2型糖尿病(T2DM)的关系。方法从2017-2019年于濮阳市第二人民医院体检的人群中选取研究对象3376人,包括男1752人,女1624人。主要采用面对面的方式进行问卷调查。采用Pearson相关分析研究静息心率与空腹血糖(FPG)、餐后2小时血糖以及糖化血红蛋白的相关性。采用logistic回归分析静息心率对T2DM的影响。采用趋势性检验分析心率加快对T2DM的发病率和影响作用的变化趋势。结果T2DM发生率为9.51%(321/3376),男性T2DM发生率为8.16%(143/1752),女性T2DM发生率为10.96%(178/1624)。男性静息心率与FPG、餐后2小时血糖、糖化血红蛋白均呈正相关(r=0.242、0.213、0.154,P<0.05),女性静息心率与FPG、餐后2小时血糖、糖化血红蛋白均呈正相关(r=0.351、0.282、0.173,P<0.05)。静息心率与T2DM的发生风险呈正相关(P<0.05)。男性心率每增加1个标准差,T2DM的发生风险增加30.2%。女性心率每增加1个标准差,T2DM的发生风险增加36.2%。T2DM发生率随着心率的加快呈现上升的趋势(P_(trend)<0.05)。结论静息心率升高可增加患T2DM的风险。

Objective To analyze the relationship between resting heart rate and type 2 diabetes mellitus(T2DM)in physical examination population.Methods A total of 3376 cases(1752 men and 1624 women)were selected from the physical examination population in the Second People’s Hospital of Puyang City from 2017 to 2019.Questionnaires were mainly conducted face to face.Pearson correlation analysis was performed to evaluate the relationship between resting heart rate and fasting blood glucose(FPG),postprandial 2-hour blood glucose and glycosylated hemoglobin.Logistic regression analysis was performed to evaluate the effect of resting heart rate on T2DM.Trend test was performed to evaluate the prevalence and effect of T2DM with the increase of heart rate.Results The incidence of T2DM was 9.51%(321/3376),8.16%(143/1752)for males and 10.96%(178/1624)for females.The resting heart rate of male was positively correlated with FPG,postprandial 2-hour blood glucose and glycosylated hemoglobin(r=0.242,0.213,0.154,P<0.05),while the resting heart rate of female was positively correlated with FPG,postprandial 2-hour blood glucose and glycosylated hemoglobin(r=0.351,0.282,0.173,P<0.05).Resting heart rate was positively correlated with the risk of T2DM(P<0.05).The risk of T2DM increased by 30.2%for every standard deviation of heart rate of male.The risk of T2DM increased by 36.2%for every standard deviation of heart rate of female.The incidence of T2DM increased with the increase of heart rate(P_(trend)<0.05).Conclusion Elevated resting heart rate could increase the risk of T2DM.