血液净化膜材料的临床发展

Clinical development of blood purification membrane materials

血液净化技术在不断发展,影响透析质量很重要的一方面是透析器膜材料。膜材料以及制备工艺的探索,是临床血液净化技术发展的重要部分。本文介绍了血液净化膜材料的历史及临床需求,概括了目前主要发展方向:以增加大分子量毒素清除来改善终末期肾衰竭患者的临床结局、提高生物相容性、减少凝血,列举了多项新型膜材料及其优势。

With the continuous development of blood purification technology,the membrane material of dialyzer is one of the most important factors affecting the quality of dialysis.The exploration of membrane materials and preparation technology is an important part of the development of clinical blood purification technology.This paper introduced the history and clinical requirements of blood purification membrane materials,and summarized the main development direction:to improve the clinical outcome of patients with end-stage renal failure by increasing the removal of toxins of large molecular weight,improve biocompatibility,and reduce coagulation.A number of new membrane materials and their advantages were listed.