综合干预对阿尔茨海默病照料者照料负担及生活质量的影响

Effect of comprehensive intervention on care burden and quality of life of Alzheimer disease caregivers

目的探讨针对阿尔茨海默病照料者的综合干预对照料者照料负担及生活质量的影响.方法于2020年1—6月在重庆市精神卫生中心老年门诊招募选取180名照料者,采用随机对照研究设计将照料者分为综合干预组(90名)和对照组(90名).研究组接受综合干预,对照组接受支持性心理干预.分别于干预前及干预后3、6个月使用照顾者负担量表(ZBI)及世界卫生组织生存质量量表简表(WHOQOL-BREF)进行评估.结果重复测量方差分析结果显示,两组照料者的ZBI、WHOQOL-BREF评分组间比较差异有统计学意义(F=4.365、5.446,P<0.05),且时间主效应(F=328.428、24.779,P<0.05)、交互作用(F=26.170、21.786,P<0.05)差异均有统计学意义.结论针对阿尔茨海默病照料者的综合干预可以降低照料负担,提高其生活质量.

Objective To explore the effect of comprehensive intervention on burden of care and quality of life of Alzheimer disease caregivers.Methods From January 2020 to June 2020,180 caregivers were recruited from the elderly clinic of Chongqing Mental Health Center.They were randomized into comprehensive intervention group(90 cases)and control group(90 cases).The study group received comprehensive intervention,and the control group received supportive psychological intervention.Zarit Caregiver Burden Interview(ZBI)and WHO Quality of Life Scale BREF(WHOQOL-BREF)were used before intervention and 3 and 6 months after intervention.Results The results of repeated measurement ANOVA showed that there were statistically significant in ZBI and WHOQOL-BREF scores between the two groups(F=4.365,5.446;P<0.05).The differences in time main effec(t F=328.428,24.779;P<0.05)and interaction(F=26.170,21.786;P<0.05)were statistically significant.Conclusions Comprehensive intervention can reduce the burden of care and improve the quality of life of Alzheimer disease caregivers.