急性酒精中毒内科急诊治疗方案及疗效探究

Study on the regimen and efficacy of emergency internal medicine treatment in acute alcoholism

目的研究急性酒精中毒内科急诊治疗方案及疗效。方法110例急性酒精中毒患者,采取抽签的方式分为实验组和对照组,每组55例。对照组患者采取纳洛酮进行治疗,实验组患者采取纳洛酮联合门冬氨酸鸟氨酸进行治疗。比较两组患者治疗效果、清醒时间与症状消失时间、不良反应发生情况。结果治疗后,实验组患者的治疗总有效率为90.91%,明显高于对照组的72.73%,差异具有统计学意义(P<0.05)。实验组患者的清醒时间(2.71±1.13)h与症状消失时间(7.79±2.21)h均短于对照组的(4.35±1.72)、(13.38±3.61)h,差异均具有统计学意义(P<0.05)。治疗后,实验组患者的不良反应发生率为7.27%,低于对照组的21.82%,差异具有统计学意义(P<0.05)。结论内科急诊治疗方案中,采用纳洛酮联合门冬氨酸鸟氨酸治疗急性酒精中毒,能够进一步减少患者急救后恢复意识时间。

Objective To study the regimen and efficacy of emergency internal medicine treatment in acute alcoholism.Methods A total of 110 patients with acute alcoholism were divided into experimental group and control group according to lottery methods,with 55 cases in each group.The control group was treated with naloxone,and the experimental group was treated with naloxone and ornithine.The therapeutic effect,recovery time of consciousness,symptom disappearance time,and occurrence of adverse reactions were compared between the two groups.Results After treatment,the total effective rate of the experimental group was 90.91%,which was obviously higher than 72.73%of the control group,and the difference was statistically significant(P<0.05).The recovery time of consciousness(2.71±1.13)h and symptom disappearance time(7.79±2.21)h of the experimental group were shorter than(4.35±1.72)and(13.38±3.61)h of the control group,and the difference was statistically significant(P<0.05).After treatment,the incidence of adverse reactions of the experimental group was 7.27%,which was lower than 21.82%of the control group,and the difference was statistically significant(P<0.05).Conclusion In emergency internal medicine treatment,combination of naloxone and ornithine aspartate to treat acute alcoholism can further reduce the recovery time of consciousness after first aid.