外阴阴道假丝酵母菌病对患者婚姻质量的影响及微生态制剂干预效果的研究

The effect of vulvovaginal candidiasis on patients′marriage quality and intervention effect of microecological preparations

目的研究外阴阴道假丝酵母菌病(VVC)对患者生活质量、婚姻质量的影响以及微生态制剂在改善VVC患者性生活质量中的应用价值。方法选择2018年1月至2019年6月在河北省第七人民医院和石家庄市第一医院就诊的62例VVC患者作为研究对象(病例组)。选择同期在河北省第七人民医院和石家庄市第一医院健康体检的30例妇女作为健康组。采用生存质量测定量表简表调查两组生活质量,采用Olson婚姻质量问卷调查两组婚姻质量。将病例组随机分为干预组和对照组,两组均给予硝酸咪康唑阴道软胶囊治疗,干预组在此基础上加用乳杆菌活菌胶囊,采用国际女性性功能评估量表对两组的性生活质量进行调查。结果在生活质量方面,病例组的心理领域、生理领域、社会关系领域及环境领域评分均低于健康组,差异具有统计学意义(P<0.01);在婚姻质量方面,病例组的婚姻满意度、夫妻交流及业余活动评分均低于健康组,差异具有统计学意义(P<0.05);在治疗后性生活质量方面,干预组的性欲望、阴道湿润度、性高潮和性交疼痛方面评分均高于对照组,差异具有统计学意义(P<0.05)。结论VVC对患者的生活质量和婚姻质量产生不良影响,微生态制剂干预有助于改善VVC患者的性生活质量。

Objective To study the effects of vulvovaginal candidiasis(VVC)on patients′quality of life and marital quality,and the application value of probiotics in improving the sexual life quality of patients with VVC.Methods 62 VVC patients admitted to the Seventh People′s Hospital of Hebei Province and the First Hospital of Shijiazhuang City from January 2018 to June 2019 were selected as the study subjects(case group),another 30 women who underwent physical examination as the health group.The quality of life of the two groups was investigated by the quality of life measurement scale,and the marital quality of the two groups was investigated by the Olson marital quality questionnaire.The case group was randomly divided into the intervention group and the control group.The two groups were treated with miconazole nitrate vaginal soft capsule,and the intervention group was added with live Lactobacillus capsule.The sexual life quality of the two groups was investigated by using the International Female Sexual Function Assessment Scale.Results In terms of life quality,the case group scored lower than the control group in the aspects of psychology,physiology,social relationship and environment(P<0.01).In terms of marriage quality,the case group scored lower than the control group in the aspects of marriage satisfaction,couple communication,and leisure activities(P<0.05).In terms of sexual life quality after treatment,the intervention group scored higher than the control group in the aspects of sexual desire,vaginal moistness,orgasm,and sexual intercourse(P<0.05).Conclusions VVC has a negative effect on the quality of life and marriage of patients,and the microecological preparations intervention is helpful to improve the quality of sexual life of patients with VVC.