PET/CT图像分割技术在NSCLC患者放疗中的应用

Application of PET/CT Image Segmentation Technology in Radiotherapy of NSCLC Patients

目的探讨PET/CT图像分割技术在非小细胞肺癌(NSCLC)患者放疗中的应用价值。方法将2016年6月至2020年2月我院的NSCLC患者118例随机分为研究组与对照组,各59例,对照组行常规CT检查,根据所得影像手动分割癌灶靶区,研究组行PET/CT检查,根据所得影像分别用手动和计算机自动化程序分割癌灶靶区,对照组以CT手动分割图像制定放疗计划,研究组以PET/CT自动分割图像制定放疗计划,比较三种分割图像所得的靶区体积与两组正常组织放疗剂量分布,记录比较两组放疗后2个月内并发症的发生情况。结果研究组手动、自动分割靶区体积均明显小于对照组(P<0.05);研究组中,PET/CT图像手动分割与自动分割的靶区体积无明显差异(P>0.05);研究组正常组织放射剂量明显低于对照组(P<0.05);放疗后2个月内研究组并发症发生率明显低于对照组(P<0.05)。结论 PET/CT图像分割技术能提高NSCLC患者癌灶靶区的定位精度,降低放疗中正常组织受累剂量,减少放疗后相关并发症。

Objective To explore the application value of PET/CT image segmentation technology in radiotherapy of patients with non-small cell lung cancer(NSCLC).Methods A total of 118 NSCLC patients in the hospital from June 2016 to February 2020 were randomly divided into study groups and control groups,59 cases in each group.The control group underwent routine CT exa mination,and the to rget volume of cancer lesions was manually segmented based on the images.The study group underwent PET/CT examination,and the target volume of cancer lesions was segmented by manual method and computer automation program based on the images.The radiotherapy plans were formulated in the control group and study group by CT manual segmentation images and PET/CT automatic segmentation images.The target volume by the three segmentation images,and the radiation dose distribution of normal tissues between the two groups were compared.The occurrence of complications within 2 months after radiotherapy were recorded and compared between the two groups.Results The to rget volume of manual and automatic segmentation in the study group was significantly smaller than that in the control group(P<0.05).In study group,there was no significant difference in the target volume between manual segmentation and automatic segmentation of PET/CT images(P>0.05).The radiation dose of normal tissue in the study group was significantly lower than that in control group(P<0.05).The incidence of complications in the study group was significa ntly lower than that in the control group within 2 months after radiotherapy(P<0.05).Conclusion PET/C image segmentation technology can improve the positioning accuracy for to rget volume of cancer lesions in NSCLC patients,decrease the dose of normal tissues involvement in radiotherapy,and reduce related complications after radiothera py.