冠心病PCI术后再发心血管不良事件危险因素分析

Analysis of Risk Factors for Recurring Adverse Cardiovascular Events after PCI in Coronary Heart Disease

目的:探讨冠心病PCI术后再发心血管不良事件危险因素。方法:选取2017年3月-2019年3月笔者所在医院实施PCI术治疗323例进行随访研究,时间1年,根据患者是否再发心血管不良事件分为再发组和未发组,收集两组患者一般临床资料和可疑危险因素,分析影响冠心病PCI术后再发心血管不良事件发生危险因素。结果:单因素分析得出,再发组和未发组患者中年龄、随访依从性、心血管家族史、合并高血压、血压控制情况、合并糖尿病、血糖控制情况、合并高脂血症、血脂控制情况、吸烟史、随访期间是否吸烟、冠心病二级预防药物依从性、冠脉病变支数、支架置入枚数比较差异有统计学意义(P<0.05)。多因素分析得出,年龄(OR=3.654,P<0.05)、随访依从性(OR=2.847,P<0.05)、心血管家族史(OR=4.154,P<0.05)、血压控制情况(OR=3.898,P<0.05)、血糖控制情况(OR=2.265,P<0.05)、血脂控制情况(OR=3.016,P<0.05)、随访期间是否吸烟(OR=4.587,P<0.05)、冠心病二级预防药物依从性(OR=5.214,P<0.05)、冠脉病变支数(OR=3.654,P<0.05)、支架置入枚数(OR=3.125,P<0.05)为影响冠心病PCI术后再发心血管不良事件独立危险因素。结论:影响冠心病PCI术后再发心血管不良事件危险因素较多,与患者血压、血糖、血脂水平控制情况,随访依从性、吸烟情况、用药依从性等均有相关性,临床中针对性进行预防和干预,对降低冠心病PCI术后心血管不良事件再发风险有重要价值。

Objective:To explore the risk factors of recurrence of adverse cardiovascular events after PCI of coronary heart disease.Method:Selected from March 2017 to March 2019,323 patients undergoing PCI treatment in our hospital were followed up for a follow-up study for 1 year.According to whether the patients had recurrence of adverse cardiovascular events,they were divided into recurring group and non-recurring group.Clinical data and suspicious risk factors were collected,analysis of risk factors that affect the occurrence of recurrent adverse cardiovascular events after PCI of coronary heart disease.Result:According to univariate analysis,age,follow-up compliance,cardiovascular family history,combined hypertension,blood pressure control status,combined diabetes,blood sugar control status,combined hyperlipidemia,and blood lipid control status,smoking history,smoking during follow-up,compliance with secondary prevention drugs for coronary heart disease,number of coronary artery lesions,and number of stents in the recurrence group and the non-recurrence group were significantly different (P<0.05).Multivariate analysis showed that age (OR=3.654,P<0.05),follow-up compliance (OR=2.847,P<0.05),cardiovascular family history (OR=4.154,P<0.05),blood pressure control status (OR=3.898,P<0.05),blood sugar control (OR=2.265,P<0.05),blood lipid control (OR=3.016,P<0.05),smoking during follow-up (OR=4.587,P<0.05),coronary heart disease grade Ⅱprevention drug compliance (OR=5.214,P<0.05),the number of coronary artery diseased branches (OR=3.654,P<0.05),and the number of stents (OR=3.125,P<0.05) were the independent risk factors for recurring adverse cardiovascular events after coronary heart disease PCI.Conclusion:There are many risk factors that affect the recurrence of cardiovascular adverse events after PCI of coronary heart disease,which are related to the control of patients’ blood pressure,blood sugar,and blood lipid levels,follow-up compliance,smoking status,medication compliance,etc.,and targeted prevention in clinical practice and intervention is of great value in reducing the risk of recurrence of adverse cardiovascular events after coronary heart disease PCI.