依托咪酯靶控输注全麻复合硬膜外麻醉对老年患者右半结肠手术的影响

Effect of Etomidate Target Controlled Infusion General Anesthesia Combined with Epidural Anesthesia on Elderly Patients Undergoing Right Hemicolectomy

目的:研究依托咪酯靶控输注全麻复合硬膜外麻醉对老年患者右半结肠手术的影响。方法:本研究选取2018年1月-2019年3月本院45例老年右半结肠癌患者,均拟行右半结肠切除术,依据麻醉方式分为观察组(n=23)和对照组(n=22)。对照组给予依托咪酯靶控输注全麻,观察组在对照组基础上复合硬膜外麻醉。比较两组麻醉前、插管时、插管后1 min、插管后5 min的心率(HR)、收缩压(SBP)、舒张压(DBP),以及苏醒时间、术后不良反应发生率。结果:两组麻醉前、插管时HR、SBP、DBP比较,差异均无统计学意义(P>0.05);插管后1、5 min,观察组HR、SBP、DBP高于对照组,差异均有统计学意义(P<0.05);观察组不良反应发生率低于对照组,苏醒时间早于对照组,差异均有统计学意义(P<0.05)。结论:依托咪酯靶控输注全麻复合硬膜外麻醉在老年右半结肠癌患者手术中,可维持心率、血压稳定,促进患者苏醒,安全性高。

Objective:To investigate the effect of Etomidate target controlled infusion general anesthesia in elderly patients undergoing right hemicolectomy.Method:A total of 45 elderly patients with right hemicolon carcinoma admitted to our hospital from January 2018 to March 2019 were selected.All patients underwent right hemicolectomy.According to the anesthesia method,they were divided into two groups,the observation group(n=23)and the control group(n=22).The control group was given Etomidate target controlled general anesthesia,and the observation group was combined with epidural anesthesia on the basis of the control group.The heart rate(HR),systolic blood pressure(SBP),diastolic blood pressure(DBP)before anesthesia,before intubation,1 min after intubation,5 min after intubation,and the recovery time and postoperative adverse reactions were compared between the two groups.Result:There were no significant difference in HR,SBP,and DBP between the two groups before anesthesia and intubation(P>0.05).The HR,SBP,and DBP in the observation group were lower than those in the control group at 1 and 5 min after intubation,the differences were statistically significant(P<0.05).The incidence of adverse reactions was lower than that of the control group,and the recovery time was earlier than that of the control group,the differences were statistically significant(P<0.05).Conclusion:Target controlled infusion of Etomidate combined with general anesthesia combined with epidural anesthesia can effectively stable the intraoperative blood pressure and heart rate,and promote the recovery of elderly patients with right hemicolon carcinoma,and it is safe.