膝关节镜下微骨折处理与去神经化联合应用治疗膝骨性关节炎的效果评估

Effect Evaluation of Knee Arthroscopic Microfracture Treatment Combined with Denervation in the Treatment of Knee Osteoarthritis

目的:探讨膝关节镜下微骨折处理与去神经化联合应用治疗膝骨性关节炎(KOA)的效果。方法:选择2019年6-12月本院收治的90例膝骨性关节炎患者为研究对象。依照红蓝球随机法将患者分为对照组与研究组,每组45例。对照组采用膝关节镜下关节清理微骨折技术治疗,研究组采用膝关节镜下微骨折处理联合去神经化治疗。比较两组患者的临床治疗效果。结果:术前,两组患者的血清IL-6、CRP指标水平比较,差异均无统计学意义(P>0.05);术后6 d,研究组的血清IL-6、CRP指标水平均低于对照组,差异均有统计学意义(P<0.05)。研究组的总有效率为97.78%,显著优于对照组的82.22%,差异有统计学意义(P<0.05)。术前,两组患者的Lysholm评分、VAS评分比较,差异均无统计学意义(P>0.05);研究组术后3、6个月的Lysholm评分均高于对照组(P<0.05);研究组术后的VAS评分显著低于对照组(P<0.05)。结论:采用膝关节镜下微骨折处理与去神经化联合应用治疗膝骨性关节炎的效果显著,患者经过治疗后炎性因子水平显著降低,膝关节功能改善效果显著,可进行推广使用。

Objective:To investigate the effect of knee arthroscopic microfracture treatment combined with denervation in the treatment of knee osteoarthritis(KOA).Method:A total of 90 patients with knee osteoarthritis admitted to our hospital from June to December 2019 were selected as the research subjects.Patients were randomly divided into control group and study group according to red-blue ball randomization method,45 cases in each group.The control group was treated with arthroscopic joint debridement microfracture technique,and the study group was treated with knee arthroscopic microfracture combined with denervation treatment.The clinical treatment effect of the two groups was compared.Result:Before operation,there were no significant differences in serum IL-6 and CRP levels between two groups(P>0.05),6 d after operation,serum IL-6 and CRP levels in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).The total effective rate of the study group was 97.78%,significantly better than 82.22%of the control group,the difference was statistically significant(P<0.05).Before operation,there were no significant differences in Lysholm score and VAS score between two groups(P>0.05);the Lysholm scores of the study group at 3 and 6 months after operation were higher than those of the control group(P<0.05),the postoperative VAS score in the study group was significantly lower than that in the control group(P<0.05).Conclusion:The combined application of knee arthroscopic microfracture treatment and denervation in the treatment of knee osteoarthritis has a significant effect,after treatment,the level of inflammatory factors in patients is significantly reduced,and the improvement effect of knee function in patients is significant,which can be popularized.