TS-1分子筛的制备及其在环己酮氨肟化工艺中的研究进展

Preparation of TS-1 Molecular Sieve and Its Research Progress in Cyclohexanone Ammoximation Process

环己酮肟作为一种重要的有机中间体,在合成纤维、医药和日用品等方面有着重要的应用。在环己酮肟众多的合成方法中,环己酮氨肟化反应由于工艺简单、条件温和且无副产物生成,从而成为研究的热点。本文以该化学反应路径为主线,从环己酮肟催化剂的制备及连续化工艺两方面的研究进展进行综述。尽管目前TS-1催化剂已取得较大的进展,但在一定程度上依然存在着催化剂成本高、反应液与催化剂分离困难、反应液堵塞催化剂孔道导致失活的现象。基于上述问题,本文对未来高效、绿色、稳定的TS-1催化剂开发的研究重点以及实现环己酮肟连续化工艺进行了展望。

Cyclohexanone oxime,an important organic intermediate,is widely applied in synthetic fiber,industrial manufacturing,medicine,and daily necessities.Many methods for the synthetic of cyclohexanone oxime are available,in which the cyclohexanone ammoximation reaction has attracted extensive attention because of the simple process,mild conditions,and no by-products.In this review,the research progress in the preparation of cyclohexanone oxime catalyst and continuous process are summarized.Although the TS-1 catalyst has made a great success at present,there are still some disadvantages such as high cost of the catalyst,difficulty in separating the reaction liquid from the catalyst,and blockage of the catalyst pores by the reaction liquid,resulting in catalyst deactivation.In addition,the research priorities for the development of efficient,green and stable TS-1 catalysts and the future research directions of the continuous cyclohexanone oxime process are prospected.