黄芩联合湿润烧伤膏治疗老年慢性顽固性皮肤溃疡临床研究

Clinical Study on Radix Scutellariae Combined with Exposed Burn Ointment for Chronic Intractable Skin Ulcer in Senile Patients

目的:观察黄芩联合湿润烧伤膏治疗老年慢性顽固性皮肤溃疡的临床效果。方法:将慢性顽固性皮肤溃疡老年患者78例按照随机数字表法为对照组与观察组各39例。全部患者均给予常规治疗,对照组加用湿润烧伤膏治疗,观察组在对照组的基础上加用黄芩水煎液湿敷治疗,治疗时间均为3个月。观察比较2组腐肉净化时间、生肌时间、创口愈合时间;观察比较2组主要症状评分及临床疗效。结果:总有效率观察组为100%,对照组为97.44%,观察组临床疗效优于对照组,经秩和检验,差异有统计学意义(P<0.05)。治疗后,观察组腐肉净化时间、生肌时间、创口愈合时间均短于对照组,差异有统计学意义(P<0.05)。治疗后,2组红肿、疼痛、腐肉、脓性分泌物等症状评分均较治疗前降低(P<0.05),且观察组各项评分低于对照组(P<0.05)。结论:黄芩水煎液联合湿润烧伤膏治疗老年慢性顽固性皮肤溃疡,可有效促进溃疡愈合,提高临床疗效。

Objective:To observe the clinical effect ofRadix Scutellariae combined with exposed burn ointment for chronic intractable skin ulcer in senile patients. Methods:A total of 78 cases of senile patients with chronic intractable skin ulcer were divided into the control group and the observation group according to the random number table method,39 cases in each group. All patients were given routine treatment;the control group was additionally treated with exposed burn ointment,and the observation group was additionally treated with water extract of Radix Scutellariae wet compressing based on the treatment of the control group. Both groups were treated for three months. Recovery time of slough, the time of tissue regeneration and the healing time of wounds were observed and compared between the two groups.The main symptom scores and clinical effect were observed and compared between the two groups. Results:The total effective rate was 100%in the observation group,and 97.44% in the control group,the clinical effect in the observation group was better than that in the control group,the difference being significant(P<0.05). After treatment,recovery time of slough,the time of tissue regeneration and the healing time of wounds in the observation group were shorter than those in the control group, the difference being significant(P<0.05). After treatment,symptom scores of redness,pain,slough and purulent secretion in the two groups were decreased when compared with those before treatment(P<0.05),and each score in the observation group was lower than that in the control group(P<0.05). Conclusion: In the treatment of chronic intractable skin ulcer in senile patients, the therapy of water extract of Radix Scutellariae combined with exposed burn ointment can effectively promote the recovery from ulcer,and improve clinical effect.