清热祛湿镇痛方联合TDP照射治疗湿热蕴结型痛风性关节炎护理研究

Nursing Study on Qingre Qushi Zhentong Prescription Combined with TDP Irradiation for Gouty Arthritis of Dampness-Heat Accumulation Type

目的:观察清热祛湿镇痛方联合TDP照射治疗湿热蕴结型痛风性关节炎的护理疗效。方法:将80例湿热蕴结型痛风性关节炎患者随机分为观察组和对照组各40例。对照组予塞来昔布胶囊口服,观察组采用清热祛湿镇痛方联合TDP照射治疗,7 d为1个疗程,观察2组患者临床症状体征、实验室监测指标、不良反应及疗效。结果:观察组总有效率为97.5%,明显高于对照组的80.0%,差异有统计学意义(χ^(2)=4.507 0,P<0.05)。2组干预前证候积分比较,差异无统计学意义(P>0.05);2组干预后证候积分较干预前降低,且观察组低于对照组,差异有统计学意义(P<0.05)。干预前,2组尿酸、血沉及C-反应蛋白比较,差异无统计学意义(P>0.05);干预后,2组的尿酸、血沉及C-反应蛋白均较干预前降低,且观察组低于对照组,差异有统计学意义(P<0.05)。2组不良反应发生率比较,差异有统计学意义(χ2=4.020 5,P<0.05)。结论:清热祛湿镇痛方联合TDP照射治疗湿热蕴结型痛风性关节炎疗效较好。

Objective:To observe the nursing effect of Qingre Qushi Zhentong prescription combined with TDP irradiation for gouty arthritis of dampness-heat accumulation type.Methods:A total of 80 cases of patients with gouty arthritis of dampness-heat accumulation type were randomly divided into the observation group and the control group,40 cases in each group.The control group was given the oral administration of celecoxib capsules,and the observation group was given Qingre Qushi Zhentong prescription combined with TDP irradiation.Both groups were treated for one course of seven days.Clinical symptoms and signs,laboratory monitoring index,adverse reactions,and curative effect were observed in the two groups.Results:The total effective rate was 97.5%in the observation group,significantly higher than that of 80.0%in the control group,the difference being significant(χ^(2)=4.5070,P<0.05).There was no significant difference being found in the comparison of syndrome score before intervention between the two groups(P>0.05).In the two groups,syndrome scores after intervention were decreased when compared with those before intervention,and the score in the observation group was lower than that in the control group,the difference being significant(P<0.05).Before intervention,when compared uric acid,erythrocyte sedimentation rate,and C-reactive protein between the two groups,there was no significance in the difference(P>0.05).After intervention,uric acid,erythrocyte sedimentation rate,and C-reactive protein in the two groups were decreased when compared with those before intervention,and the three indexes in the observation group were lower than those in the control group,the difference being significant(P<0.05).The comparison of the incidence of adverse reactions between the two groups showed significance in the difference(χ^(2)=4.0205,P<0.05).Conclusion:The therapy of Qingre Qushi Zhentong prescription combined with TDP irradiation has a good curative effect in the treatment of gouty arthritis of dampness-heat accumulation type.