摘要
失眠是临床上常见疾病,对患者学习工作生活均造成一定困扰。目前认为失眠与GABA、MT、5-HT等抑制性神经递质含量不足,HPA轴过度活跃,炎症因子等密切相关。中医认为,失眠的病机总属阳盛阴衰,阴阳失交,病位在心,与肝、脾、肾密切相关。本文对失眠机理进行综述,旨在为深入研究失眠的机理提供依据,为临床精准诊治提供参考。
Insomnia is a common disease in clinic,which causes some trouble to patients'study,work and life.At present,it is believed that insomnia is closely related to insufficient content of inhibitory neurotransmitters such as GABA,MT,5-HT,overactive HPA axis,inflammatory factors and so on.According to traditional Chinese medicine,the pathogenesis of insomnia is always yang exuberance with yin debilitation,yin-yang disharmony,the disease is located in the heart,closely related to the liver,spleen and kidney.This paper reviews the mechanism of insomnia in order to provide a basis for in-depth study of the mechanism of insomnia and provide reference for clinical accurate diagnosis and treatment.
作者
卢玉俊
于小刚
代晶晶
李应东
Lu Yujun;Yu Xiaogang;Dai Jingjing;LiYingDong(Affiliated Hospital of Gansu University of Traditional Chinese Medicine,Gansu Lanzhou 730000;Gansu University of Traditional Chinese Medicine,Gansu Lanzhou 730000)
出处
《中国社区医师》
2021年第14期8-9,共2页
Chinese Community Doctors
基金
国家重点研发计划资助项目:慢性失眠中医诊疗新方案及机制研究(项目编号:2018YFC1705600)
失眠及其与更年期综合征、高血压、老年轻度认知障碍等相关病症的关系及综合治理方案研究(课题编号:2018YFC1705604)~~
关键词
失眠
病因病机
作用机理
中西医
研究进展
Insomnia
Etiology and pathogenesis
Mechanism
Traditional Chinese and western medicine
Research progress