分析不同麻醉深度对老年腹腔镜手术患者脑功能的影响

To analyze the effect of different depth of anesthesia on brain function in elderly patients with laparoscopic surgery

目的:分析不同深度麻醉对老年腹腔镜手术患者脑功能的影响。方法:2018年11月-2020年8月收治实施腹腔镜全麻手术的患者88例,按照麻醉深度进行分组。浅麻醉44例,麻醉深度指数为47~64,纳入甲组;深麻醉449例,麻醉深度指数为35~45,纳入乙组。比较两组患者认知功能。结果:甲组术后24 h、72 h认知功能评分均低于乙组,差异有统计学意义(P<0.05);甲组术后24 h、72 h肿瘤坏死因子-α(TNF-α)、白介素-10(IL-10)、SI00β等血清炎性因子指标水平均高于乙组,差异有统计学意义(P<0.05);乙组麻醉满意度高于甲组,差异有统计学意义(P<0.05)。结论:在老年腹腔镜手术患者中采用深麻醉,可以在提高麻醉安全性的同时,降低麻醉手术对患者认识功能的损伤。

Objective:To analyze the effect of different depth of anesthesia on brain function in elderly patients with laparoscopic surgery.Methods:From November 2018 to August 2020,88 patients undergoing laparoscopic general anesthesia were selected and divided into groups according to the depth of anesthesia.44 cases of light anesthesia were included in group A,anesthesia depth index was 47 to 64.449 cases of deep anesthesia were included in group B,anesthesia depth index was 35 to 45.We compared the cognitive function between the two groups.Results:In group A,the cognitive function scores at 24 hours and 72 hours after operation were lower than those in group B,the difference was statistically significant(P<0.05).In group A,the levels of TNF-α,IL-10 and SI00βat 24 hours and 72 hours after operation were higher than those in group B,the difference was statistically significant(P<0.05).The satisfaction of anesthesia in group B was higher than that in group A,the difference was statistically significant(P<0.05).Conclusion:In elderly patients with laparoscopic surgery,deep anesthesia can improve the safety of anesthesia and reduce the damage of cognitive function.