间歇性断食联合多元化管理模式对超重及肥胖人群减重效果的研究

Effect of intermittent fasting combined with diversified management mode on the weight control in overweight and obese patients

目的探讨间歇性断食联合多元化管理模式对超重/肥胖人群的减重效果。方法选择2019年1—12月首都医科大学附属北京潞河医院就诊的超重/肥胖患者110例,按照随机数字表法分为对照组和干预组,每组各55例。对照组实施常规间歇性断食模式,干预组实施间歇性断食联合多元化管理模式的减重干预,包括采用搭配营养膳食、合理运动、健康教育、互联网监测及心理疏导等综合手段。观察12周后两组的BMI、腰围、腰臀比、血脂、饥饿感、饱腹感、满足感的变化情况。结果剔除退出、失访、不严格执行间歇性断食的患者,最终对照组和干预组各纳入52例患者,两组一般资料比较差异无统计学意义(P>0.05)。对照组和干预组干预前后各指标(体质量、腰围、腰臀比、BMI、血脂)及饥饿感、饱腹感、食物满足感比较,差异均有统计学意义(P<0.05),且干预组改善效果优于对照组。结论间歇性断食与多元化管理相结合,有效改善了减重患者的体质量、腰围、腰臀比、BMI、血脂各指标,增强食物饱腹感及满足感,减少饥饿感,提高了患者的减重依从性。

Objective To explore the effect of intermittent fasting combined with diversified management mode on the weight control in overweight and obese patients.Methods A total of 110 overweight or obese patients were divided into two groups.The control group took routine intermittent fasting mode,while the intervention group combined intermittent fasting with diversified management mode,including nutritional diet,exercise training,health education,remote internet monitoring and psychological counseling.The changes of BMI,waist circumference,waist to hip ratio,blood lipid components,feelings of hunger and fullness were assessed in the two groups after 12-week managements.Results The patients who withdrew,lost to follow up and did not strictly implement intermittent fasting were excluded,104 patients were enrolled in the study,52 cases in each group.There were significant changes of the above indices in both groups after 12-week of management,and the changes in the intervention group were significantly better than those in the control group(P<0.05).Conclusions Intermittent fasting combined with diversified management modes can effectively decrease the body weight,waist circumference,waist to hip ratio,BMI and blood lipid,as well as decrease the feelings of hunger and increase the feelings of fullness,can improve the patient's compliance.