基于Tobit模型分析长沙市高中女生HPV九价疫苗支付意愿及其影响因素

Willingness to pay for nine-valent HPV vaccine and its associates among senior high school girl students in Changsha city:a Tobit model-based analysis

目的了解湖南省长沙市高中女生对人乳头瘤病毒(HPV)九价疫苗的支付意愿情况,分析影响高中女生HPV九价疫苗支付的因素。方法于2018年10—11月采用多阶段整群抽样法和调查问卷方式,收集湖南省长沙市某区782名高一、高二女生HPV九价疫苗的知晓情况和支付意愿资料,采用Tobit模型分析高中女生疫苗支付意愿的影响因素。结果782名高中女生在调查前听说过HPV及HPV疫苗的分别有245人(31.33%)、273人(34.91%)。731名(93.48%)高中女生愿意为接种HPV九价疫苗支付一定的费用,44.36%的女生对九价疫苗的支付愿意低于市场价格,九价疫苗(单剂)的平均支付意愿为1244元。Tobit模型结果显示,父亲文化程度、自觉疾病易感性对疫苗支付意愿呈正向影响,对疫苗价格看法呈负向影响。结论长沙市高中女生父亲的文化程度、对疫苗价格的看法以及自觉疾病易感性是影响支付意愿的重要因素。决策者和有关机构应重视疫苗的宣传与接种规划,提高适龄群体对疫苗与疾病的认识及疫苗可及性。

Objective To examine the willingness to pay for nine-valent human papillomavirus(HPV)vaccine and its influencing factors among senior high school girl students.Methods Using multistage cluster sampling,we recruited 900 grade one and two girl students in three senior high schools in a district of Changsha city,Hunan province and conducted a self-administered anonymous questionnaire survey to collect the students′information on the awareness about and willingness to pay for nine-valent HPV vaccine during October–November 2018.Tobit regression model was adopted to analyze influencing factors of the willingness among the students.Results Of the 782 students with valid response,245(31.33%)and 273(34.91%)reported the awareness about HPV and HPV vaccine;731(93.48%)expressed the willingness to have self-paid vaccination of nine-valent HPV vaccine and presented an average acceptable amount of money of 1244 yuan(RMB)for one dose of the vaccine;44.36%presented an acceptable price lower than the market value for one dose of the vaccine.The results of Tobit model analysis indicated that paternal education and self-rated susceptibility to HPV infection have positive impacts on the willingness to pay for the vaccine;while the perception on vaccine price has a negative effect on the willingness.Conclusion Paternal education,the perception on vaccine price,and self-rated susceptibility to HPV infection are important factors for willingness to pay for HPV vaccine vaccination among senior high school girl students in Changsha city;the results suggest that health education on HPV infection and significance of HPV vaccine need to be promoted among the students.