郑州地区高尿酸血症流行病学研究

Epidemiology Research of Hyperuricemia in Zhengzhou

目的调查郑州地区普通成年人群高尿酸血症(HUA)的患病率和流行病学特点,探讨高尿酸血症的危险因素。方法选取2019年6月份在郑州市第一人民医院体检科进行体检的1000例人员作为研究对象,采用随机抽样的方法进行问卷调查。分析普通成年人群高尿酸血症的发病原因和危险因素。结果单因素分析结果表明:郑州地区普通成年人群的问卷调查资料主要从性别、体重指数、高碳高糖饮食、每餐过饱、饮酒、熬夜、工作压力大、血脂异常等原因进行调查,女性人员的甘油三酯、总胆固醇、低密度脂蛋白、高密度脂蛋白、血尿酸的数据指标均低于男性人员(P<0.05);多因素Logistic分析结果表明:年龄、体重指数、高碳高糖饮食、每餐过饱、饮酒、熬夜、工作压力大、血脂异常等均为高尿酸血症的独立危险因素。结论郑州地区普通成年人群高尿酸血症患者主要以男性为主,多与不良生活习惯有关。

Objective To investigate the prevalence and epidemiological characteristics of hyperuricemia in the general adult population in Zhengzhou,and to explore the risk factors of hyperuricemia.Methods A total of 1000 people who had physical examination in the department of physical examination of Zhengzhou First People's Hospital in June 2019 were selected as the research objects,the method of random sampling was used to conduct a questionnaire survey.To analyze the causes and risk factors of hyperuricemia in the general adult population.Results The results of single factor analysis showed that the questionnaire data of the general adult population in Zhengzhou area were mainly investigated from the factors of sex,body mass index,high-carbon and high-sugar diet,overeating,drinking,staying up late,working pressure,abnormal blood lipid,etc.the data indexes of triglyceride,total cholesterol,low-density lipoprotein,high-density lipoprotein and serum uric acid in female were lower than those in male(P<0.05).Multivariate Logistic analysis showed that age,body mass index,high-carbohydrate and high-sugar diet,overeating,drinking,staying up late,working pressure and dyslipidemia were all independent risk factors for hyperuricemia.Conclusion The majority of adult patients with hyperuricemia in Zhengzhou area are male,and most of them are related to bad living habits.