摘要
抑郁症是一种常见的精神障碍疾病,具有高致残率、高自杀率和治疗难度大的特点。目前研究发现,肠道菌群与抑郁症存在密切的联系,而且微生物标记物在抑郁症诊断中的作用也逐渐被认识。肠道菌群通过作用于神经、免疫、内分泌等系统影响大脑功能,其可能在抑郁症发生发展中起至关重要的作用。随着研究的不断深入,肠道菌群标记物有望填补抑郁症生物学诊断的空缺。
Depression is a common mental disorder,which has the characteristics of high disability rate,high suicide rate and difficult to treat.Now studies have found a close relationship between gut microbiota and depression,and the role of microbial markers in the diagnosis of depression is increasingly being recognized.Gut microbiota influences brain function by acting on nerve,immune,endocrine and other systems,which may play a crucial role in the occurrence and development of depression.With the gradual advancement of research,microbial markers are expected to fill the blanks in the biological diagnosis of depression.
作者
韩雪雪
车荣波
翟金国
陈敏
Han Xuexue;Che Rongbo;Zhai Jinguo;Chen Ming(School of Mental Health,2 Shandong Collaborative Innovation Center for Diagnosis,Treatment and Behavioral Interventions of Psychotic Disorders,Shandong Key Laboratory of Behavioral Medicine,Research Institute of Mental Health,Jining Medical University,Jining 272013,China)
出处
《中华诊断学电子杂志》
2021年第2期141-144,共4页
Chinese Journal of Diagnostics(Electronic Edition)
基金
济宁医学院教师科研扶持基金(JY2017JS007)。
关键词
肠道菌群
抑郁症
诊断
作用机制
Gut microbiota
Depression
Diagnosis
Mechanism
