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肌肉骨骼超声对强直性脊柱炎患者外周附着点病变的诊断价值 被引量:1

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摘要 目的探讨肌肉骨骼超声在强直性脊柱炎(AS)患者评估附着点病变的临床意义。方法应用肌肉骨骼超声检查40例AS患者双下肢9个附着点(包括跖底筋膜止点、跟腱止点、股四头肌肌腱止点、股骨和胫骨内外髁韧带附着点、髌韧带起点和止点),同时采用酶联免疫吸附法检测患者血清白介素17(IL-17)、核转录因子-κB配体受体激动剂(RANKL)及肿瘤坏死因子-α(TNF-α)含量,分析患者超声评估附着点病变与血清IL-17、RANKL及TNF-α相关性。结果 720个附着点中超声发现275处(38.2%)附着点病变,最常见的病变是骨侵蚀,超声评估附着点存在骨侵蚀个数及附着点炎个数与AS患者血清IL-17及RANKL均呈正相关(r=0.479、0.379、0.416、0.354,均P<0.05)。结论肌肉骨骼超声是观察AS附着点炎和骨侵蚀的安全有效的检查方法。
出处 《现代实用医学》 2021年第4期461-463,共3页 Modern Practical Medicine
基金 宁波市第二医院华美研究基金(2017HMKY31)。
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