中医药防治过敏性鼻炎-哮喘综合征研究述评

Evaluation of studies of prevention and treatment of combined allergic rhinitis and asthma syndrome with TCM

过敏性鼻炎-哮喘综合征(CARAS)是典型的变态反应性疾病,也是呼吸系统的常见病及难治症,其患病率高,发病机制复杂,治疗手段有限,且易反复发作。中医药以整体辨证、综合治疗为特色,在此病临床诊治中有重要价值。本文对CARAS的病理机制、病因病机及中医药治疗研究等方面进行了文献述评,认为"特禀质"是CARAS患者的主要体质类型,伏邪干肺是其核心病机,"辨体-辨病-辨证"诊疗模式是其临床防治思路,随机对照试验及大样本真实世界研究是其未来研究方向。

The combined allergic rhinitis and asthma syndrome(CARAS)is not only a typical allergic disease but a common and refractory disorder of the respiratory system with high prevalence rate and complex pathogenesis.Due to limited therapies,CARAS is prone to recurrent attacks.Traditional Chinese medicine(TCM),characterized by overall pattern differentiation and systemic therapy,has been proved to be valuable in the treatment of CARAS.Literature on CARAS was reviewed in terms of its etiology,pathogenesis,and treatment with TCM.Based on that,it is concluded that the special-diathesis constitution is the primary constitution of patients with CARAS,that latent pathogen attacks the lung is the core pathogenesis,constitution-disease-pattern differentiation is the way of diagnosis and treatment in clinical prevention and treatment,and the randomized controlled trial and large-sample real-world research would be the directions of future clinical study.