CT、阴道超声对卵巢良恶性肿瘤的诊断效能及与肿瘤标志物相关性分析

Diagnostic Efficiency of CT and Transvaginal Ultrasonography in Benign and Malignant Ovarian Tumors and Their Correlation with Tumor Markers

选取我院80例卵巢良恶性肿瘤患者作为研究对象,经病理检查证实的卵巢癌患者40例作为观察组,同期卵巢肿瘤患者40例作为对照组,均行能谱CT检查、阴道彩超检查。结果显示,观察组静脉期碘浓度、标准化碘浓度、斜率、PSV、血清CA125、CA199、AFP水平高于对照组,PI、RI低于对照组(P<0.05);静脉期碘浓度、标准化碘浓度、斜率、PSV与血清CA125、CA199、AFP水平呈正相关,PI、RI与血清CA125、CA199、AFP水平呈负相关(P<0.05);联合鉴别诊断卵巢良恶性肿瘤的AUC值为0.913,高于任一参数单独诊断。CT、阴超技术可分别从病灶内部成分及血流形态方面提供诊断信息,二者联合在卵巢良恶性肿瘤鉴别诊断中具有较高价值。

A total of 80 patients with benign and malignant ovarian tumors in our hospital were selected as research objects.After being confirmed by pathological examination,40 patients with ovarian cancer served as the observation group,and 40 patients with ovarian tumor during the same period served as the control group.Energy spectrum CT examination and vaginal color Doppler ultrasound examination were performed.The results showed that the intravenous iodine concentration,standardized iodine concentration,slope,PSV,serum CA125,CA199,and AFP levels of the observation group were higher than those of the control group,and PI and RI were lower than those of the control group(P<0.05).Intravenous iodine concentration,standardized iodine concentration,slope,PSV and serum CA125,CA199,AFP levels were positively correlated,PI,RI and serum CA125,CA199,AFP levels were negatively correlated(P<0.05).The AUC value of the combined differential diagnosis of ovarian benign and malignant tumors was 0.913,which was higher than any single parameter diagnosis.It is suggested that CT and vaginal ultrasonography can provide diagnostic information from the internal components of the lesion and the blood flow morphology.The combination of the two has a high value in the differential diagnosis of ovarian benign and malignant tumors.