IC/TLC在COPD患者病情评估及风险预测中的研究进展

Reserch advances of IC/TLC in the assessment and risk prediction of COPD patients

慢性阻塞性肺疾病(COPD)是一组以不完全可逆的气流受限为特征的慢性气道疾病,其发病率高,严重危害健康。COPD患者精确的病情评估及风险预测是COPD疾病管理的关键,目前多采用慢性阻塞性肺疾病全球倡议(GOLD)推荐的分组方法进行病情评估。近年来,深吸气量/肺总量(IC/TLC)这一肺功能指标在COPD的病情评估及风险预测方面显示出较多优势,IC/TLC被证实为肺过度充气的一项敏感指标,同时在评估患者的运动耐力、治疗疗效及预测疾病预后等方面均有其价值。本文对IC/TLC近年的研究进展作一综述,以推动其在临床中的应用。

Chronic obstructive pulmonary disease(COPD)is a group of chronic airway diseases characterized by incomplete reversible airflow obstruction.Accurate disease assessment and risk prediction of COPD patients are the key to COPD disease management.Currently,the grouping method recommended by global initiative for chronic obstructive lung disease is often used for disease assessment.In recent years,the inspiratory capacity to total lung capacity(IC/TLC),an indicator of lung function,has shown many advantages in the disease evaluation and risk prediction of COPD.IC/TLC has been proved to be a sensitive indicator of lung hyperinflation,and has its value in the evaluation of patients'exercise endurance,therapeutic efficacy,and the prediction of disease prognosis.In this paper,the research progress of IC/TLC in recent years is reviewed to promote its clinical application.