摘要
Dear Editor,The second wave of the coronavirus disease(COVID-19)pandemic has recently appeared in Europe.Most European countries,such as France,Germany,and Italy,have announced the implementation of a new round of epidemic prevention and control measures.However,no clinical drug or vaccine has been approved for the treatment of COVID-19.The interim results of the solidarity therapy trial coordinated by the World Health Organization(WHO)indicated that remdesivir,hydroxychloroquine,lopina-vir/ritonavir,and interferon appear to have little or no effect on the 28-day mortality of hospitalized patients or the hospitalization process of new COVID-19 patients.Therefore,there is an urgent need to develop new drugs against COVID-19.
基金
This work was supported by the Strategic Priority Research Program of CAS(XDB29010000)
the National Science and Technology Major Project(2018ZX10101004 and 2018ZX10733403)
the National Key Research and Development Program of China(2020YFC0845900,2016YFD0500300 and 2016YFE0205800)
the National Natural Science Foundation of China(82041016,81871658,81673358 and 21807109)
a grant from the Bill&Melinda Gates Foundation and and is partially supported by the Yanqi Lake Meeting organized by the Academic Divisions of CAS
Y.S.is supported by the Youth Innovation Promotion Association of CAS.
