摘要
异柠檬酸脱氢酶(isocitrate dehydrogenase,IDH)是胶质瘤基因诊断的重要内容之一,也是影响胶质瘤患者治疗及预后的关键因素之一。MR成像、多模态成像及影像组学的多种影像征象及组学特征与IDH基因表型相关。作者就胶质瘤IDH基因型与影像学研究进展予以综述。
Isocitrate dehydrogenase(IDH)is not only one of the important contents of glioma gene diagnosis,but also one of the key factors affecting the treatment and prognosis of glioma patients.A variety of imaging features and radiomic features of MRI imaging,multimodal imaging and radiomics are associated with the phenotype of IDH gene.This article reviews the progress in the study of IDH genotypes and imaging of gliomas.
作者
蒋健
张学凌
周俊林
JIANG Jian;ZHANG Xueling;ZHOU Junlin(Second Clinical school,Lanzhou University,Lanzhou 730030,China;Department of Radiology,Lanzhou University Second Hospital,Lanzhou 730030,China;Key Laboratory of Medical Imaging of Gansu Province,Lanzhou 730030,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2021年第5期103-106,共4页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金(编号:82071872)
兰州大学第二医院“萃英科技创新计划”应用基础研究项目(编号:CY2017-MS03)。
关键词
异柠檬酸脱氢酶基因型
胶质瘤
功能磁共振成像
多模态成像
影像组学
isocitrate dehydrogenase genotype
glioma
functional magnetic resonance imaging
multi-modal imaging
radiomics
