不同胎龄及不同性别早产儿出生后24 h内桡动脉血红细胞参数参考范围

Reference range of red blood cell parameters of radial artery within 24 hours after birth of premature infants with different gestational ages and genders

目的建立不同胎龄及不同性别早产儿出生后24 h内红细胞参数参考范围。方法选取2018年1月1日至2019年12月31日所有于吉林大学白求恩第一医院产科分娩、出生后住入新生儿重症监护病房以及吉林省内其他转诊的早产儿资料进行回顾性分析,根据纳入标准和排除标准筛选,所有早产儿均于出生后24 h内完成桡动脉采血,根据血常规结果,分析统计不同胎龄及不同性别早产儿红细胞参数参考范围。结果随胎龄增加,红细胞数、血红蛋白、红细胞压积、平均血红蛋白浓度逐渐升高,红细胞平均体积、平均血红蛋白量逐渐降低(P均<0.05);34周≤胎龄<37周的早产儿部分红细胞参数具有性别差异,与男婴相比,女婴红细胞数、血红蛋白、红细胞压积、平均红细胞体积较高(P均<0.05);23周≤胎龄<28周组早产儿红细胞数为2.58×10^(12)~5.45×10^(12)/L,28周≤胎龄<34周组早产儿红细胞数为2.97×10^(12)~5.86×10^(12)/L,34周≤胎龄<37周组中男婴红细胞数为3.38×10^(12)~5.83×10^(12)/L,女婴红细胞数为3.18×10^(12)~5.89×10^(12)/L。不同胎龄、不同性别早产儿红细胞分布宽度差异无统计学意义,为14.8~20.6%。结论本研究建立了23周≤胎龄<37周早产儿出生后24 h内红细胞参数参考范围,不同胎龄、不同性别早产儿部分红细胞参数具有差异性。

Objective To establish the reference range of red blood cell parameters within 24 hours after birth of premature infants with different gestational ages and genders.Methods According to the inclusion criteria and exclusion criteria,a retrospective analysis was performed in premature infants who were admitted to the neonatal intensive care unit from January 1,2018 to December 31,2019.These newborns were delivered in the obstetrics department of our hospital or came from other parts of Jilin Province.All of their radial artery blood were collected within 24 hours after birth.According to the blood examination results,we analyzed reference range of red blood cell parameters of these premature infants.Results With the increase of gestational age,the number of RBC,HGB,HCT,MCHC gradually increases and the number of MCV,MCH gradually decreases.There are differences in some red blood cell parameters of premature infants with 34 week≤gestational age<37 week between different genders.Compared with boys,the number of RBC,HGB,HCT and MCV in girls were higher.The number of RBC in premature infants with 23 week≤gestational age<28 week and 28 week≤gestion age<34 week are 2.58×10^(12)-5.45×10^(12)/L and 2.97×10^(12)-5.86×10^(12)/L respectively.In the group of premature infants with 34 week≤gestion age<37 week,the number of RBC in boys is 3.38×10^(12)-5.83×10^(12)/L,while the number of RBC in girls is 3.18-5.89×10^(12)/L.There're no difference in RDW among preterm infants with different gestational ages and genders,which is 14.8%-20.6%.Conclusions The study established the reference range of red blood cell parameters of 23 w≤gestational age<37 w premature infants within 24 hours after the birth and explored the differences in red blood cell parameters of premature infants with different gestational ages and genders.