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右美托咪定椎管内麻醉对患者应激反应的影响 被引量:3

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摘要 目的观察右美托咪定椎管内麻醉对患者应激反应的影响。方法选取2018年2月-2019年12月红河州滇南中心医院/个旧市人民医院收治的行椎管内手术患者114例,采用随机数字表法分为试验组和对照组各57例。对照组施以丙泊酚,试验组施以右美托咪定,比较2组患者用药前(T0)、用药后20 min(T1)、30 min(T2)、60 min(T3)与术毕(T4)时的心率(HR)、平均动脉压(MAP)、去甲肾上腺素(NE)及肾上腺素(AD),观察2组不良反应。结果 T0时,2组患者的HR、MAP、NE及AD无差异(P>0.05);T1、T2、T3与T4时,试验组患者的HR、MAP明显低于对照组(P<0.05);T1、T2时,2组患者的NE、AD无差异(P>0.05),但T3与T4时试验组患者NE、AD水平均明显低于对照组(P<0.05);试验组患者的不良反应总发生率为5.26%,低于对照组的22.81%(χ^(2)=7.270,P=0.007)。结论右美托咪定可有效降低椎管内麻醉手术患者的应激反应,具有积极影响,还可降低不良反应发生率。
作者 刘翠美
出处 《临床合理用药杂志》 2021年第10期93-94,共2页 Chinese Journal of Clinical Rational Drug Use
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  • 1王冰.盐酸右美托咪定辅助镇静对老年患者行椎管内麻醉术后睡眠功能的影响[J].世界临床医学,2017,11(13):16-16. 被引量:4
  • 2Mantz J, Josserand J, Hamada S. Dexmedetomidine: new insights [ J]. Eur J Anaesthesiol, 2011,28 ( 1 ) : 3 - 6.
  • 3Bekker A, Sturaitis M, Bloom M, et al. The effect of dexmedeto- midine on perioperative hemodynamics in patients undergoing cra- niotomy [J]. Anesth Analg, 2008, 107(4) : 1340 -1347.
  • 4Schnabel A, Meyer-Friel3em CH, Reichl SU, et al. Is intraopera- tive dexmedetomidine a new option for postoperative pain treat- ment? A meta-analysis of randomized controlled trials [J]. Pain, 2013, 154(7) : 1140 -1149.
  • 5Kim SY, Kim JM, Lee JH, et al. Efficacy of intraoperative dexmedetomidine infusion on emergence agitation and quality of re- covery after nasal surgery [J]. Br J Anaesth, 2013, 111 (2) : 222 - 228.
  • 6Blaudszun G, Lysakowski C, Elia N, et al. Effect of perioperative systemic or2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials [ J ]. Anesthesiology, 2012, 116 (6) : 1312 - 1322.
  • 7Ngwenyama NE, Anderson J, Hoemschemeyer DG, et al. Effects of dexmedetomidine on propofol and remifentanil infusion rates during total intravenous anesthesia for spine surgery in adolescents [ J]. Paediatr Anaesth, 2008, 18 (12) : 1190 - 1195.
  • 8Bakhamees HS, E1-Halafawy YM, E1-Kerdawy HM, et al. Effects of dexmedetomidine in morbidly obese patients undergoing laparo- scopic gastric bypass [ J ]. Middle East J Anesthesiol, 2007, 19(3) : 537 -551.
  • 9Patel CR, Engineer SR, Shah BJ, et al. Effect of intravenous in- fusion of dexmedetomidine on perioperative haemodynamic changes and postoperative recovery: A study with entropy analysis [ J]. In- dian J Anaesth, 2012, 56(6) : 542 -546.
  • 10Gerlach AT, Murphy CV. Dexmedetomidine-associated bradycar- dia progressing to pulseless electrical activity: case report and re- view of the literature [ J ]. Pharmacotherapy, 2009, 29 ( 12 ) : 1492.

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