人体测量学指标与R-VQS技术测量的颈动脉弹性指标的相关性

Correlations between anthropometric parameters and carotid elasticity by real-time vascular quantification

目的探讨人体测量学指标与超声全息血管硬度分析(R-VQS)技术测量的颈动脉弹性指标之间的相关性及在预测心血管疾病风险中的价值。方法563例体检者,按男女性别分组。采集各位受试者的人体测量学指标[体重指数(BMI)、腰围(WC)、身体形态指数(ABSI)、身体圆润指数(BRI)、内脏脂肪指数(VAI)],并应用R-VQS技术检测受试者颈动脉弹性参数脉搏波传导速度(PWV),分析人体测量学指标与PWV的相关性,并采用线性回归分析PWV的预测因素。结果⑴男性BMI、WC、ABSI、BRI、VAI、PWV参数均高于女性(P<0.05);⑵男、女性BMI、WC、ABSI、BRI、VAI参数与SBP、DBP、TC、TG呈正相关,与HDL呈负相关(P<0.05);⑶男性糖尿病史、高血压史可预测PWV(β=0.110、0.101,P均<0.05),女性糖尿病史、高血压史及吸烟史是PWV的预测因素(β=0.061、0.095、0.067,P均<0.05);⑷在矫正糖尿病、高血压、吸烟相关因素后,ABSI和VAI在男性群体中可预测颈动脉PWV(β=0.078、0.068,P<0.05);BMI、WC、ABSI、BRI、VAI在女性群体中是颈动脉PWV的预测因素(β=0.131、0.123、0.204、0.153、0.196,P<0.05)。结论ABSI和VAI在男、女性群体中均是颈动脉PWV的预测因素,可作为临床简便评估肥胖并预测心血管疾病风险的人体测量学指标。R-VQS技术可早期反映颈动脉血管壁弹性变化,是一种方便、实时、快捷的检查方法。

Objective This study aimed to investigate the relationships between anthropometric parameters and carotid elasticity by real-time vascular quantification stiffness technique(R-VQS),and to identify the predictive value of anthropometric parameters for cardiovascular disease risk.Methods A total of 563 adults were recruited for this study and were divided into two groups by gender.The anthropometric indices[body mass index(BMI),waist circumference(WC),a body shape index(ABSI),body round index(BRI),and visceral adiposity index(VAI)]were calculated.R-VQS technique was used to assess the parameters of carotid elasticity:pulse wave velocity(PWV).The correlations between the anthropometric indices and PWV were analyzed.Linear regression was used to analyze the predictive factors of PWV.Results⑴The BMI,WC,ABSI,BRI,VAI and PWV were higher in men than those in women(P<0.05);⑵In men and women,all the anthropometric parameters positively correlated with systolic blood pressure(SBP),diastolic blood pressure(DBP),total cholesterol(TC),triglycerides(TG),and negatively correlated with high-density lipoprotein(HDL)(P<0.05);⑶diabetes mellitus(DM)and hypertension history were predictors of PWV in men(β=0.110,0.101,respectively,P<0.05);DM,hypertension history and smoking status were predictors of PWV in women(β=0.061,0.095,0.067,respectively,P<0.05);⑷After adjusting for diabetes,hypertension and smoking,ABSI and VAI were predictors of PWV in men(β=0.078,0.068,P<0.05);BMI,WC,ABSI,BRI and VAI were predictive factors of carotid PWV in women(β=0.131,0.123,0.204,0.153,0.196,P<0.05).Conclusions Among the anthropometric indexes,ABSI and VAI have good correlations with carotid elasticity in wen and women,represented by PWV.These results suggest that ABSI and VAI may be convenient,highly cost-effective and simple parameters for obesity and are associated with cardiovascular disease(CVD)risk in clinical practice.R-VQS is a convenient,real-time and rapid technique for the early assessment of the carotid elasticity.