冠心病患者颈动脉超声参数与左室舒张功能的相关性分析

Analysis of Correlation between Carotid Ultrasound Parameters and Left Ventricular Diastolic Function in Patients with Coronary Heart Disease

[目的]探讨冠心病患者颈动脉超声参数与左室舒张功能的相关性。[方法]收集2019年1月至2020年3月在本院诊治的24例心肌梗死患者作为A组,并收集同期在本院诊治的30例不稳定性心绞痛患者(B组)和26例稳定性心绞痛患者(C组),三组患者均接受颈动脉超声检查和左室舒张功能检测。对比三组患者的颈动脉超声参数[颈总动脉硬化度(β)、颈动脉顺应性(AC).弹性系数(EP)、脉搏波传导速度(PEVβ)]和左室舒张功能[二尖瓣E峰/组织多普勒E峰(E/Em)、二尖瓣E峰/左室血流传导速度(E/Vp)、二尖瓣E峰/A峰(E/A)、肺静脉反流速度(PVAR).E峰线速时间(DT)]情况;分析颈动脉超声参数与左室舒张功能的关系。[结果]A组患者β、AC、EP、PEVβ.IMT、E/Em、E/A.DT、E/Vp.PVAR值均显著高于B组和C组,且B组上述参数值也显著高于C组,其差异均有统计学意义(P<0.05);相关性分析结果显示:冠心病患者颈动脉超声参数与左室舒张功能各参数水平间两两均呈正相关(P<0.05)。[结论]冠心病患者的颈动脉超声参数与左室舒张功能参数呈显著相关性,颈动脉超声各参数越高可能提示左室舒张功能越差。临床可依据颈动脉超各参数变化预判冠心病患者的左室舒张功能变化。

[Objective]To investigate the relationship of carotid artery ultrasound parameters with left ven-tricular diastolic funetion in patients with coronary heart disease.[Methods]F rom January 2019 to March 2020,24 patients with myocardial infarction treated in our hospital were included in the group A.and 30 patients with unstable angina and 26 patients with stable angina treated in the hospital in the same period were enrolled in the group B and group C,respectively.All patients in three groups received carotid ultrasound examination and left ventricular diastolic function measurement.The carotid artery ultrasound parameters[Common carotid artery stifness(β),carotid artery compliance(AC),elastic cofficient(EP),pulse wave velocity(PEVβ)]and left ventricular diastolie function[Mitral valve E peak/Tissue Doppler E peak(E/Em),Mitral valve E peak/Left ventricular blood flow velocity(E/Vp),Mitral valve E peak/A peak(E/A),pulmonary venous re-flux velocity(PVAR),E peak linear velocity time(DT)]of patients in the three groups were compared to an-alyze the relationship between carotid ultrasound parameters and left ventricular diastolic function.[Results]Theβ,AC,EP,PEVβ,IMT,E/Em,E/A,DT,E/Vp and PV AR values of group A were higher than those of group Band C(P<0.05).while the above parameter values of group B were higher than those of group C(P<0.05).The correlation test results showed that there was a positive correlation bet ween the carotid ultra-sound parameters and the levels of left ventricular diastolic function in patients with coronary heart disease(P<0.05).[Conclusion]The carotid ultrasound parameters of patients with coronary heart disease are correlated with left ventricular diastolic function.The higher the carotid ultrasound parameters,the worse the left ven-tricular diastolic function.Clinically.the changes of left ventricular diastolic function in patients with coronary heart disease can be predicted based on the changes of various parameters of the carotid artery,which may be of positive significance for guiding early left ventricular diastolic function evaluation and formulation of treatment plan.