^(18)F-FDG PET/CT显像在多发性骨髓瘤诊疗中的研究进展

Research progress of^(18)F-FDG PET/CT imaging in the diagnosis and treatment of multiple myeloma

多发性骨髓瘤(MM)是一种克隆性浆细胞异常增生的恶性疾病,多发于老年人,其发病率居恶性血液病的第二位,目前在我国其发病率呈逐年上升的趋势。^(18)F-氟脱氧葡萄糖(FDG)PET/CT显像能够在分子水平上提供恶性肿瘤的增殖和代谢情况等信息,已有的研究结果表明,其在MM的诊断、分期、疗效监测和预后评估等方面具有重要意义。笔者对^(18)F-FDG PET/CT显像在MM诊疗中的研究进展进行综述。

Multiple myeloma(MM)is a malignant disease of clonal plasma cell hyperplasia,which occurs mostly in the elderly.The incidence of MM ranks second in hematological malignancies and is currently on the rise in China year by year.^(18)F-fluorodeoxyglucose(FDG)PET/CT imaging can provide information on the proliferation and metabolism of malignant tumors at the molecular level.Existing studies have proved that^(18)F-FDG PET/CT is of great significance in the diagnosis,staging,monitoring of efficacy and prognostic evaluation of MM.This paper reviews the research progress of^(18)F-FDG PET/CT imaging in the diagnosis and treatment of MM.