雌激素联合甲硝唑栓剂及乳酸菌制剂治疗绝经后萎缩性阴道炎的临床研究

The Efficacy of Estrogen Combined with Metronidazole and Lactobacillus in Postmenopausal Atrophic Vaginitis

目的探究雌激素联合甲硝唑栓剂及乳酸菌制剂治疗绝经后萎缩性阴道炎的疗效。方法将2017年9月至2019年9月前来就诊的绝经后萎缩性阴道炎患者150例,随机分为A组(雌激素+甲硝唑栓剂)、B组(雌激素+乳酸菌阴道胶囊)和C组(雌激素+甲硝唑栓剂+乳酸菌阴道胶囊),治疗后对比不同组别之间的治疗效果。结果按照上述分组治疗后,A组治疗有效率86.00%,B组治疗有效率72.00%,C组治疗有效率96.00%,c2=16.12,P=0.003,各组之间具有明显差异。结论雌激素、甲硝唑栓剂以及乳酸菌制剂三者联合应用相较于雌激素联合甲硝唑栓剂或雌激素联合乳酸菌制剂在治疗绝经后萎缩性阴道炎方面有更好的疗效。

Objective To explore the efficacy of estrogen combined with metronidazole and lactobacillus in the treatment of postmenopausal atrophic vaginitis.Methods Postmenopausal atrophic vaginitis patients who came to the hospital during September 2017 to September 2019 were divided into group A(estrogen combined with metronidazole),B(estrogen combined with lactobacillus)and C(estrogen combined with metronidazole and lactobacillus),and the efficacy of each therapy was compared after treatment.Results After treatment,the efficacy of group A was 86.00%,with group B 72.00%and group C 96.00%,c2=16.12,P=0.003.There were differences among these three groups.Conclusion For treating postmenopausal atrophic vaginitis,estrogen combined with metronidazole and lactobacillus is better than estrogen combined with metronidazole or estrogen combined with lactobacillus.