我国猪急性腹泻综合征冠状病毒研究进展

Research advances in swine acute diarrhea syndrome coronavirus in China

猪急性腹泻综合征冠状病毒(SADS-CoV),一种来源于蝙蝠的新型冠状病毒,于2017年1月在华南地区首次被发现,是冠状病毒科(coronaviridae)、α冠状病毒属(alphacoronavirus)的新成员。SADS-CoV主要感染5日龄以内新生仔猪,对初生仔猪的危害严重。SADS-CoV可引发引起剧烈呕吐、腹泻、严重脱水而导致新生仔猪急性死亡,短短4个月造成广东省4个猪场将近25 000头新生仔猪死亡,给养猪业带来巨大的经济损失。本研究基于SADS-CoV的国内外研究进展,对SADS-CoV的起源、流行概况、病原学、病毒的诊断方法、潜在的跨物种传播风险与防控方面进行综述,以期为该病的预防和控制提供参考。

Swine acute diarrhea syndrome coronavirus(SADS-CoV) is a new member of the alphacoronavirus of the family coronaviridae, which was first discovered in Southern China in 2017.It has been identified that SADS-CoV originates from bats and mainly infects newborn piglets within five days of age and causes acute vomiting, diarrhea, and severe dehydration, which leads to death eventually.Nearly 25 000 newborn piglets died across four farms within four months in Guangdong Province, which has caused substantial economic losses to the swine industry.Based on the research progress of SADS-CoV at home and abroad, this paper reviewed the origin of virus, epidemic situation, etiology and the diagnostic methods of virus, and potential risk of cross-species transmission, the prevention and control of the disease, hoping to provide references for the prevention and control of SADS.