维生素D缺乏对新生儿健康影响的研究进展

Research progress on the effects of vitamin D deficiency on neonatal health

维生素D是一种脂溶性维生素,不仅具有抗菌抗炎、免疫调节的作用,还参与了人体多种细胞的增殖、分化、凋亡。维生素D缺乏已成为全球性的公共卫生问题,孕妇维生素D缺乏对母婴二人均有直接影响,是新生儿健康的危险因素之一。本文主要综述了维生素D的代谢及生理功能、影响新生儿维生素D水平的因素、维生素D缺乏与新生儿疾病的关系、维生素D水平评价标准、维生素D的推荐剂量及膳食补充。以期达到提高孕妇补充维生素D的意识的目的,为提高我国新生儿生存质量提供保障,同时为新生儿相关疾病的预防和治疗提供新思路。

Vitamin D is a kind of fat-soluble vitamin, which not only has antibacterial, anti-inflammatory and immunomodulatory effects, but also participates in the proliferation, differentiation and apoptosis of a variety of human cells. Vitamin D deficiency has become a global public health problem. Vitamin D deficiency in pregnant women has a direct impact on both mother and infant, which is one of the risk factors of neonatal health. This paper mainly reviewed the metabolism and physiological function of vitamin D, the factors affecting the level of vitamin D in newborns, the relationship between vitamin D deficiency and neonatal diseases, the evaluation standard of vitamin D level, and the recommended dose of vitamin D and dietary supplement, so as to improve the awareness of pregnant women to supplement vitamin D, provide guarantee for improving the quality of life of newborns in China, and provide new ideas for the prevention and treatment of neonatal related diseases.