采用红光照射与更昔洛韦治疗带状疱疹患者的临床效果

Clinical Effect of Red Light Irradiation and Ganciclovir in the Treatment of Patients with Herpes Zoster

目的探讨带状疱疹患者采用更昔洛韦与红光照射进行治疗的临床效果。方法选取2018年10月至2019年10月沈阳市苏家屯区中心医院皮肤科收治的带状疱疹患者300例作为研究对象,采用随机数字表法将其分为对照组与观察组,各150例。对照组采用更昔洛韦对患者进行静脉滴注治疗,观察组在对照组基础上使用高能窄谱光动力治疗仪对患者进行红光照射治疗,比较两组患者的治疗效果。结果观察组治疗有效率高于对照组,差异有统计学意义(P<0.05);观察组水疱结痂、疼痛缓解以及疼痛消失时间短于对照组,差异有统计学意义(P<0.05);治疗后,两组患者VAS评分降低,且观察组低于对照组,差异有统计学意义(P<0.05)。结论使用更昔洛韦与红光照射治疗带状疱疹患者可快速缓解临床症状,有效减轻疼痛。

Objective To explore the clinical effects of ganciclovir and red light irradiation in the treatment of patients with herpes zoster. Methods From October 2018 to October 2019, a total of 300 patients with herpes zoster admitted to the Department of Dermatology, Sujiatun District Central Hospital in Shenyang City were selected as the research objects, and were randomly divided into a control group and an observation group, with 150 cases in each group. The control group were treated with ganciclovir intravenously, and the observation group was treated with red light irradiation with a high-energy narrow-band photodynamic therapy instrument plus intravenous ganciclovir. The clinical treatment effects of the 2 groups were compared. Results The effective rate of treatment in the observation group was higher than that in the control group, and the difference was statistically significant(P<0.05);the observation group was shorter than the control group with vesicle crusting, pain relief and pain disappearing time, and the difference was statistically significant(P<0.05);Later, the VAS scores of the 2 groups of patients decreased, and the observation group was lower than the control group, the difference was statistically significant(P<0.05). Conclusion The use of ganciclovir and red light irradiation to treat patients with herpes zoster can quickly relieve clinical symptoms and effectively relieve pain.