早期乳腺癌患者行保乳术和改良根治术的疗效分析

Efficacy analysis of breast-conserving surgery and modified radical mastectomy for early breast cancer

目的探讨早期乳腺癌行保乳术的安全性和有效性。方法 100例早期乳腺癌患者,根据手术方式不同分为保乳术组和改良根治术组,每组50例。改良根治术组患者行改良根治术治疗,保乳术组患者行保乳术治疗。比较两组手术相关指标、术后患侧胸部美观度、并发症发生情况及术后局部复发率、远处转移率、生存率。结果保乳术组患者的手术时间(112.23±5.65)min、住院时间(6.68±1.74)d、引流时长(6.67±2.16)d短于改良根治术组的(120.30±9.23)min、(8.52±2.25)d、(8.52±2.25)d,术中出血量(34.23±13.77)ml、引流量(245.25±146.69)ml少于改良根治术组的(47.79±5.23)、(305.86±28.01)ml,差异具有统计学意义(P<0.05)。保乳术组患者的术后患侧胸部美观度90%(45/50)高于改良根治术组的0,差异具有统计学意义(P<0.05)。两组并发症发生率比较差异无统计学意义(P>0.05)。两组术后局部复发率、远处转移率和生存率比较,差异均无统计学意义(P>0.05)。结论在掌握手术指征及保乳技巧前提下,治疗早期乳腺癌采取保乳术不仅保留了乳房,且提高了患者的生活质量,减轻了患者的心理负担,值得在临床中大力推广。

Objective To discuss the safety and effectiveness of early breast-conserving surgery.Methods A total of 100 patients with early breast cancer were divided into breast-conserving surgery group and modified radical mastectomy group according to different surgical methods,with 50 cases in each group.Modified radical mastectomy group was treated with modified radical mastectomy,and the breast-conserving surgery group was treated with breast-conserving surgery.The surgical related indicators,postoperative breast aesthetics of the affected side,occurrence of complications,postoperative local recurrence rate,distant metastasis rate and survival rate were compared between the two groups.Results The operation time(112.23±5.65)min,hospitalization time(6.68±1.74)d,drainage time(6.67±2.16)d of breast-conserving group were shorter than(120.30±9.23)min,(8.52±2.25)d,(8.52±2.25)d of modified radical mastectomy group,and intraoperative blood loss(34.23±13.77)ml and drainage volume(245.25±146.69)ml were less than(47.79±5.23)and(305.86±28.01)ml of modified radical mastectomy group.All the difference was statistically significant(P<0.05).The postoperative breast aesthetics of the affected side 90%(45/50)of breast-conserving surgery group was higher than 0 of modified radical mastectomy group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in incidence of complications between the two groups(P>0.05).There was no statistically significant difference in postoperative local recurrence rate,distant metastasis rate and survival rate between the two groups(P>0.05).Conclusion Under the premise of mastering the surgical indications and breast-conserving techniques,breast-conserving surgery for early breast cancer can not only preserve the breast,but also improve the quality of life and reduces the psychological burden of the patients,which is worthy of vigorous promotion in clinical practice.