摘要
自身免疫性溶血性贫血(Autoimmune hemolytic anemia,AIHA)是异基因造血干细胞移植术(Allogeneic hematopoietic stem cell transplantation,allo-HSCT)后一种少见但严重的并发症。移植后早期出现AIHA的机制目前尚未阐明,治疗手段有限,往往预后不佳。本文收集并分析了我院收治的1例原发病为骨髓增生异常综合征(myelodysplastic syndrome,MDS)行allo-HSCT后发生AIHA的临床特点、诊治方法、治疗选择和转归,并结合文献分析总结其临床特征,以期了解allo-HSCT后AIHA的发病机制及防治。
Autoimmune hemolytic anemia(AIHA)is a rare but serious complication after allogeneic hematopoietic stem cell transplantation(allo-HSCT).The mechanism of early occurrence of AIHA after transplantation has not yet been elucidated,treatment options are limited,and the prognosis is often poor.This article collects and analyzes the clinical characteristics,diagnosis and treatment methods,treatment options,and outcomes of AIHA after allo-HSCT in a case of primary myelodysplastic syndrome(MDS)who were admitted to our hospital.Combined with literature analysis,this article also analyzes and summarizes its clinical characteristics,in order to understand the pathogenesis and prevention of AIHA after allo-HSCT.
作者
祝宁宁
胡慧瑾
赵越超
叶宝东
ZHU Ningning;HU Huijin;ZHAO Yuechao;YE Baodong(The First Clinical College of Zhejiang Chinese Medical University,Hangzhou310053,China;Department of Hematology,The First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou310006,China)
出处
《中国现代医生》
2021年第11期142-146,共5页
China Modern Doctor
基金
国家自然科学基金项目(81774092)。
