卵巢恶性Brenner瘤多发转移死亡一例并文献复习

Ovarian Malignant Tumor of Brenner:A Case Report and Literature Review

回顾性分析2019年4月青岛大学附属医院收治的1例首发症状表现为持续性腰部疼痛伴心慌的卵巢恶性Brenner瘤(malignant Brenner tumor,MBT)的年轻女性患者并复习相关文献,总结目前国内外诊断及治疗该病的进展。该例患者经腹腔穿刺活检组织病理学及免疫组织化学标记确诊,免疫组织化学显示GATA3阳性,细胞角蛋白7(CK7)阳性。该类疾病临床表现及影像学表现缺乏特异性,诊断依靠组织病理学及免疫组织化学标记物。晚期患者临床表现多样,要注意各脏器的功能情况,在抢救治疗过程中应注意全身机能状态,避免感染发生,尽可能提高患者的生存质量。

A case of young female patients with ovarian malignant Brenner tumor(MBT)was reported.The progress of diagnosis and treatment was summarized.This patient was accompanied by nontypical symptoms of persistent lumbar pain and palpitation.The diagnosis of MBT was confirmed by histopathology,and immunohistochemical markers including the positive GATA3 and CK7,with the tissue of abdominal biopsy.In this paper,the related literatures were also reviewed.The clinical manifestations and imaging manifestations of MBT are unspecific,so the diagnosis is mainly based on histopathological and immunohistochemical markers.The clinical manifestations of patients with advanced stage are diverse,and the functional state of whole body should be brought attention.Two important things are to avoid infection and to improve the life quality as far as possible.