摘要
目的:探讨病人主观整体营养状况评估量表(PG-SGA)、营养风险筛查2002(NRS-2002)在鼻咽癌(NPC)放疗病人营养评估中的价值及其与癌因性疲乏(CRF)的相关性。方法:选取2017年1月—2019年9月在我院就诊的77例NPC病人作为研究对象。于病人放疗前1周内、放疗2周后、放疗4周后、放疗6周后采用PG-SGA、NRS-2002对其进行营养筛查,采用多维疲劳症状量表(MFSI-SF)对其CRF进行评定。结果:NPC病人不同时间点的MFSI-SF、PG-SGA、NRS-2002得分及血白蛋白水平比较,差异均有统计学意义(均P<0.001),且各时间点两两比较,差异亦有统计学意义(均P<0.05)。放疗前1周内、放疗2周后、放疗4周后、放疗6周后病人PG-SGA得分与血白蛋白水平的一致性评价Kappa值依次为0.737(P<0.001)、0.506(P<0.001)、0.368(P<0.001)、0.384(P<0.001),NRS-2002得分与血白蛋白水平的一致性评价Kappa值依次为0.504(P<0.001)、0.319(P<0.001)、0.115(P=0.002)、0.026(P=0.354)。放疗前1周内、放疗2周后、放疗4周后、放疗6周后病人PG-SGA得分与MFSI-SF得分均呈正相关(r_(放疗前1周内)=0.848,r_(放疗2周后)=0.804,r_(放疗4周后)=0.750,r_(放疗6周后)=0.511),NRS-2002得分与MFSI-SF得分均呈正相关(r_(放疗前1周内)=0.763,r_(放疗2周后)=0.597,r_(放疗4周后)=0.511,r_(放疗6周后)=0.394)。结论:强化营养状态对CRF具有重要意义,PG-SGA是筛查接受调强放射治疗的NPC病人营养状态的首选工具。
Objective:To explore value of Patient-Generated Subjective Global Assessment(PG-SGA)and Nutritional Risk Screening 2002(NRS-2002)in nutritional assessment of patients with nasopharyngeal carcinoma(NPC)undergoing radiotherapy and their correlation with cancer related fatigue(CFR).Methods:A total of 77 NPC patients in our hospital from January 2017 to September 2019 were selected as research subjects.Nutritional status was screened by PG-SGA、NRS-2002 within 1 week before radiotherapy,2 weeks after radiotherapy,4 weeks after radiotherapy,and 6 weeks after radiotherapy.CRF was evaluated by Multidimensional Fatigue Symptom Inventory(MFSI-SF).Results:Differences among scores of MFSI-SF,PG-SGA,NRS-2002 and albumin concentration at different time points of NPC patients were statistically significant(all P<0.001),and differences between two groups at each time point were statistically significant(all P<0.05).Kappa value of consistency evaluation between PG-SGA scores and albumin concentration within 1 week before radiotherapy,2 weeks after radiotherapy,4 weeks after radiotherapy,and 6 weeks after radiotherapy were 0.737(P<0.001),0.506(P<0.001),0.368(P<0.001),0.384(P<0.001).And Kappa value of consistency evaluation between NRS-2002 scores and albumin concentration were 0.504(P<0.001),0.319(P<0.001),0.115(P=0.002),0.026(P=0.354).The patient's PG-SGA scores and MFSI-SF scores within 1 week before radiotherapy,2 weeks after radiotherapy,4 weeks after radiotherapy,and 6 weeks after radiotherapy were positively correlated(rwithin 1 week before radiotherapy=0.848,r_(2 weeks after radiotherapy)=0.804,r_(4 weeks after radiotherapy)=0.750,r6 weeks after radiotherapy=0.511),and NRS-2002 scores and MFSI-SF scores were positively correlated(rwithin 1 week before radiotherapy=0.763,r_(2 weeks after radiotherapy)=0.597,r_(4 weeks after radiotherapy)=0.511,r_(6 weeks after radiotherapy)=0.394).Conclusion:It had great significance for CRF to enhance nutritional status.And PG-SGA was the first choice for screening nutritional status of NPC patients undergoing intensity modulated radiation therapy.
作者
罗勤
陈美
沈建芳
LUO Qin;CHEN Mei;SHEN Jianfang(Jinshan Hospital of Fudan University,Shanghai 201508 China)
出处
《护理研究》
北大核心
2021年第10期1751-1756,共6页
Chinese Nursing Research
关键词
主观整体营养状况评估量表
营养风险筛查2002
鼻咽癌
营养评估
癌因性疲乏
护理
Patient-Generated Subjective Global Assessment
Nutritional Risk Screening 2002
nasopharyngeal carcinoma
nutritional assessment
cancer related fatigue
nursing