肺癌患者围术期预防性抗凝情况调查分析

Investigation and analysis of perioperative prophylactic anticoagulation in patients with lung cancer

目的癌症患者为静脉血栓栓塞症的高危人群,了解肺癌患者围术期的预防性抗凝情况,旨在为临床更好的预防肺癌患者术后并发VTE提供客观依据。方法回顾性分析2017年1月~2019年6月行肺癌手术的患者共173例,纳入患者的一般资料、Caprini评分及预防性抗凝情况。结果在所有患者中,Caprini评分≥5分有172例,均有药物性抗凝指征,但实际药物性预防性抗凝64例,抗凝率37.21%;住院期间仅有1例在未行药物性抗凝情况下出现急性肺栓塞。结论肺癌患者围术期预防性抗凝率不高,但有逐年上升趋势。虽然有临床症状的VTE发病率不高,但确切的VTE发病率不详,为了更好的改善肿瘤患者的生存质量及生存期,需进一步提高肺癌患者围术期的预防性抗凝率。

Objective Cancer patients have a high risk of venous thromboemlism.In order to provide objective basis for clinical prevention of VTE after lung cancer surgery,here we take an invetigation for the perioperative prophylactic anticoagulation of patients with lung cancer in our hospital.Methods 173 patients who underwent lung cancer surgery in our hospital between January 2016 and June 2019 were analysed retrospectively.Their general informations,Caprini scores and the situations of prophylactic anticoagulation were reviewed.Results There were 172 patients with Caprini score≥5 and all of them had drug prophylactic anticoagulation index.But indeed,only 64 patients were treated with prophylactic anticoagulation.The prophylactic anticoagulant rate was 37.21%.Only one patient developed acute pulmonary embolism without prophylactic anticoagulation during hospitalization.Conclusion The perioperative prophylactic anticoagulation rate of patients with lung cancer in our hospital is not high,but it has an increasing trend year by year.Although the incidence of VTE with clinical symptoms is not high,but the exact incidence of VTE is unknown.In order to improve the quality of life and the survival time of patients with lung cancer,we need to further improve the perioperative prophylactic anticoagulation rate.