通腑醒神汤联合茴拉西坦对急性脑出血患者炎症指标及血浆脑钠肽水平的影响

Effects of Tongfu Xingshen Decoction and Aniracetam on Inflammatory Indexes and Plasma BNP Levels in Patients with Acute Cerebral Hemorrhage

目的:探讨通腑醒神汤联合茴拉西坦对急性脑出血患者炎症指标及血浆脑钠肽(BNP)水平的影响。方法:选取郑州市第十六人民医院2019年3月—2020年1月收治的97例急性脑出血患者,根据随机数表法将其分为对照组48例与观察组49例。对照组予以茴拉西坦治疗,观察组在此基础上予以通腑醒神汤治疗,两组均持续治疗14d,对比两组炎症指标[超敏C反应蛋白(hs-CRP)及白介素-6(IL-6)]、血浆BNP水平、神经功能[神经功能缺损评分(NIHSS)]。结果:治疗后,两组血清hs-CRP、IL-6、BNP水平均下降,观察组低于对照组(P<0.05);治疗后,两组NIHSS评分均下降,观察组NIHSS评分低于对照组(P<0.05)。结论:通腑醒神汤联合茴拉西坦治疗急性脑出血患者,能够有效减轻炎症反应,提高神经功能,改善预后。

Objective:To investigate the effect of Tongfu Xingshen decoction combined with aniracetam on inflammation indexes and plasma brain natriuretic peptide(BNP)levels in patients with acute cerebral hemorrhage.Methods:A total of 97 patients with acute cerebral hemorrhage treated in the hospital from March 2019 to January 2020 were selected and divided into control group with 48 cases and observation group with 49 cases according to the random number table method.The control group was treated with Aniracetam,and the observation group was treated with Tongfu Xingshen Decoction on this basis.Both groups were treated with continuous treatment for 14 days.The inflammatory indicators[high-sensitivity C-reactive protein(hs-CRP)and interleukin-6(IL-6)],plasma BNP level,neurological function[neural impairment score(NIHSS)]of the two groups were compared.Results:After treatment,the serum hs-CRP,IL-6,and BNP levels of the two groups decreased,and the observation group was lower than the control group(P<0.05).After treatment,the NIHSS scores of the two groups decreased,and the NIHSS scores of the obser-vation group were lower than the control group(P<0.05).Conclusion:Tongfu X ingshen Decoction combined with Aniracetam in the treatment of patients with acute cerebral hemorrhage can effectively reduce inflammatory response,improve nerve function,and improve prognosis.