单孔胸腔镜手术对肺癌患者疼痛应激及术后并发症的影响

Effect of single port thoracoscopic surgery on pain stress and postoperative complications in patients with lung cancer

目的探讨单孔胸腔镜手术治疗肺癌的临床效果。方法选取2019年5月至2020年5月我院收治的104例肺癌患者,随机将其分为研究组与对照组,每组52例。研究组开展单孔胸腔镜手术,对照组开展三孔胸腔镜手术。比较两组的肿瘤标志物、疼痛应激指标水平及术后并发症发生情况。结果术后3 d,两组的血清CYFRA21-1、CEA及CA125水平均较术前显著降低(P<0.05),但两组间无显著差异(P>0.05)。术后3 d,两组的血清5-HT及NE水平均较术前显著升高,但研究组低于对照组(P<0.05)。研究组的术后并发症总发生率为7.69%,略低于对照组的15.38%(P>0.05)。结论单孔胸腔镜手术应用于肺癌患者中可有效调节肿瘤标志物水平,且术后疼痛感较弱,不会引发更多术后并发症。

Objective To explore the clinical effect of single port thoracoscopic surgery in the treatment of lung cancer.Methods One hundred and four patients with lung cancer treated in our hospital from May 2019 to May 2020 were selected and randomly divided into study group and control group,with 52 cases in each group.The study group was treated with single port thoracoscopic surgery,while the control group was treated with three port thoracoscopic surgery.The tumor markers,pain stress indexes levels and postoperative complications were compared between the two groups.Results Three days after operation,the levels of serum CYFRA21-1,CEA and CA125 in the two groups were significantly lower than those before operation(P<0.05),but there were no significant differences between the two groups(P>0.05).Three days after operation,the serum 5-HT and NE levels of the two groups were significantly higher than those before operation,but those of the study group were lower than the control group(P<0.05).The total incidence of postoperative complications in the study group was 7.69%,which was slightly lower than 15.38%in the control group(P>0.05).Conclusion Single port thoracoscopic surgery applied in lung cancer patients can effectively adjust the levels of tumor markers,with weak postoperative pain,and it will not cause more postoperative complications.