揿针对癌症骨转移疼痛调控作用的临床观察

Clinical observation on the control of pain from bone metastasis of cancer

目的:探讨分析揿针治疗癌症骨转移疼痛的效果及调控作用。方法:选取2020年1月至2020年10月收治的120例癌症骨转移疼痛患者分为治疗组和对照组,对照组采用常规西药治疗,治疗组采用常规西药联合揿针治疗,比较两组患者治疗前、治疗后5 d、10 d、15 dVAS及NRS评分、镇痛效果,治疗前、治疗后15 d实验室指标。结果:治疗前两组VAS、NRS评分无显著性差异(P>0.05);治疗后治疗组5 d、10 d、15 dVAS及NRS评分较对照组均显著下降(P<0.05),治疗组镇痛有效率显著优于对照组(95.00%vs 83.33%)(P<0.05);治疗前两组ET-1、TNF-α、IL-6指标水平无显著性差异(P>0.05),治疗后15 d治疗组ET-1、TNF-α、IL-6指标水平较对照组下降更显著(P<0.05)。结论:揿针治疗癌症骨转移疼痛可对穴位产生长时间、持续性的刺激,同时也可以调控参与癌痛发生的相关因子水平,共同作用起到缓解患者疼痛的目的,值得推广。

Objective:To explore and analyze the effect and regulation of pressing needles in the treatment of cancer bone metastasis pain.Method:120 patients with cancer bone metastasis pain admitted from February 2020 to February 2020 were selected and divided into treatment group and control group.The control group is given conventional western medicine treatment;the treatment group was combined with acupuncture treatment.The VAS and NRS scores of the two groups before treatment,5 d,10 d,15d and 15d after treatment,analgesic effect,laboratory indicators before and 15d after treatment were compared between the two groups.Results:VAS,NRS before treatment the scores were not significantly different(P>0.05).After treatment,the 5d,10d,15d VAS and NRS scores of the treatment group were significantly lower than those of the control group(P<0.05),and the effective rate of analgesia in the treatment group was significantly better than that of the control group(95.00%vs83)33%(P<0.05),there was no significant difference in the levels of ET-1,TNF-α,IL-6 between the two groups before treatment(P>0.05),and 15 days after treatment,the ET-1,TNF-α,the level of IL-6 index decreased more significantly than those of the control group(P<0.05).Conclusion:Pressing acupuncture treatment of cancer bone metastasis pain can produce long-term and continuous stimulation of acupoints,and it can also regulate the related factors involved in cancer pain.Level and the joint effect can alleviate the pain of patients,which is worthy of promotion.