摘要
Invasive fungal diseases(IFD)impact morbidity,mortality,hospital stay and healthcare costs in critically ill patients,constituting an unmet medical need.1 Pathogenic fungi rarely cause IFD in immunocompetent individuals but become life-threatening in cases of immunodeficiency,young infants,disrupted mucosal barriers or polyantibiotic therapy,highlighting the role of immune surveillance in IFD control.^(2)
基金
This work was supported by the Spanish Ministerio de Economía y Competitividad(SAF-2016-80535-R)
co-financed by the European Development Regional Fund“A way to achieve Europe”to F.L.M.V.-d-A.,C.C.,S.C.-L.,I.S.,and E.C.are recipients of fellowships from the Ministerio de Economía y Competitividad(BES-2014-069237
BES-2017-082107)
the Ministerio de Educación Cultura y Deporte(FPU15/02897)
the Fundação para a Ciência e a Tecnologia(SFRH/BD/75738/2011
and the European Community Seventh Framework Program(BIOTRACK,FP7/2007/2013
229673).
