摘要
New strains of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)with several dominant mutations in the spike protein have been identified recently,and crucial issues associated with the possible reinfection of recovered patients and the efficiencies of vaccines designed based on epidemic strains in early 2020.
基金
supported by the National Special Research Program of China for Important Infectious Diseases(2018ZX10302103 and 2017ZX10202102)
the Special 2019-nCoV Program of Natural Science Foundation of China(NSFC)(82041002)
the Special 2019-nCoV Project of National Key Research and Development Program of China(2020YFC0841400)
the Special 2019-nCoV Project of Research and Development Program of G uangdong(2020B111123001)
the Important Key Program of NSFC(81730060)
the Joint-innovation Program in Healthcare for Special Scientific Research Projects of Guangzhou(201803040002)to H.Z
This work was also supported by the National Postdoctoral Program for Innovative Talents and the General Program of China Postdoctoral Science Foundation(BX20190398 and 2019M663215)to X.M.