摘要
It is believed that the adaptive immune system responds to nonself according to its specificity and memory properties,whereas the innate immune system lacks adaptive characteristics.The specificity of the adaptive immune response is based on irreversible changes in the DNA sequence by retroposons encoding site-specific recombinases,which generate unlimited numbers of receptors to allow B lymphocytes and T lymphocytes to specifically recognize antigens.
基金
supported by grants from the National Key R&D Program of China(2017YFA0105002,2017YFA0104402,Y.Z.)
the Chinese Government 13th Five-Year Plan(2017ZX10201101)
the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16030301,Y.Z.)
the National Natural Science Foundation for General and Key Programs(C81530049,C81130055,C31470860,U1738111,Y.Z.)
the Fundamental Research Funds for the Central Universities(2018-JYBZZ-XJSJJ004,Z.C.).
