磁共振影像技术在心脏淀粉样变性中的应用

Magnetic resonance imagin in patients with cardiac amyloidosis

系统性淀粉样变性是一组异质性疾病,其共同的特征是不同来源的错误折叠蛋白质沉积在全身多个组织器官.心脏是常见受累器官之一,心脏淀粉样变性的严重程度是影响患者预后的决定性因素.磁共振技术因具有出色的空间分辨率和高组织对比度,在心脏淀粉样变性的形态学评估、诊断、危险分层和预后评估等方面具有极为广阔的应用前景.本文就磁共振相关技术在心脏淀粉样变性中的应用进展作一综述.

Systemic amyloidosis is a group of heterogeneous disorders, Its common feature is the deposition of misfolded proteins from different sources in multiple tissues and organs throughout the body.When the heart is involved, it is called cardiac amyloidosis, and its severity is a decisive factor in patient’s prognosis.Because of its excellent spatial resolution and high tissue contrast, magnetic resonance imaging has a broad application prospect in morphological assessment, diagnosis, risk stratification and prognosis assessment of cardiac amyloidosis.In this article, application progress of nuclear magnetic resonance in cardiac amyloidosis is reviewed.