急性冠脉综合征与部分炎性因子的关系

Relationship between Acute Coronary Syndromes and Some Biomarkers

急性冠脉综合征(ACS)是一种心血管急症。中性粒细胞/淋巴细胞比率(NLR)、血小板/淋巴细胞比率(PLR)、红细胞分布宽度(RDW)、C-反应蛋白(CRP)和脂蛋白-磷脂酶A2(LP-PLA2)是反映全身或局部炎症的生物标志物,可能参与ACS炎症进展、血栓形成及斑块破裂过程,与ACS和ACS的PCI术后死亡风险相关。深入了解和合理应用这些炎性指标有助于从炎症机制早期防治ACS和再发心肌梗死。

Acute coronary syndrome(ACS)is a cardiovascular emergency.Neutrophilst and lymphocyte ratio(NLR),platelet and lymphocyte ratio(PLR),red blood cell distribution width(RDW),C-reactive protein(CRP)and lipoprotein-phospholipase A2(LP-PLA2)are biomarkers which can reflect systemic or local inflammation,they may participate in the inflammation,thrombus formation and plaque rupture process in ACS,associated with the risk of ACS and PCI postoperative death.Understanding and rational application of these inflammatory markers are helpful for the early prevention and treatment of ACS and recurrent myocardial infarction from the inflammatory mechanism.