中药单体成分抗白假丝酵母作用的研究进展

Research Progress on Monomer Components in Traditional Chinese Medicine Against Candida Albicans

近年来,随着抗菌药物、糖皮质激素药物的不合理使用,以白假丝酵母为主的真菌感染发病率不断升高,且其对传统抗真菌药物的耐药问题日益严峻。中药单体作为抗白假丝酵母药物具有来源广泛、价格低廉、副反应轻微等特点。文中综述从不同机制对各种常见中药单体成分抗白假丝酵母的作用文献,并对其研究进展做了分析,为探寻白假丝酵母相关感染患者的临床治疗新思路提供参考。

ABSTRCA T In recent years, with the irrational use of antibiotics and glucocorticoids, the incidence rate of fungal infection mainly caused by Candida albicans, whose resistance to conventional antifungal drugs is becoming more and more serious, is increasing. As anti-Candida albicans drugs, traditional Chinese medicine monomers have the characteristics of wide sources, low price and mild side effects. This paper reviews the literatures on the mechanisms of various common Chinese medicine monomers against Candida albicans, and analyzes the research progress, so as to provide a reference for exploring new clinical treatment ideas for patients with Candida albicans related infection.